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Decreased nitric oxide synthesis in rats with chronic renal failure

Kim SW, Lee JU, Paek YW, Kang DG, Choi KC

The present study was aimed at investigating whether an altered role of nitric oxide (NO) is involved in chronic renal failure (CRF). Rats were subjected to 5/6 nephrectomy and kept...
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Altered renal expression of nitric oxide synthase isozymes in spontaneously hypertensive rats

Kim SW, Moon KH, Lee SC, Kim NH, Kang DG, Lee JU, Choi KC, Kang YJ

  • KMID: 759080
  • Korean J Intern Med.
  • 1999 Jan;14(1):21-26.
OBJECTIVES: The present study was aimed at exploring whether the pathogenesis of hypertension is related with an altered expression of nitric oxide synthase (NOS) isozymes, i.e., bNOS, iNOS...
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Erythropoietin does not affect nitric oxide system in rats with chronic renal failure

Kim SW, Lee JU, Kang DG, Jung K, Kim NH, Suh SP, Choi KC, Kang YJ

We investigated to see whether an altered role of nitric oxide (NO) system is involved in erythropoietin (EPO)-induced hypertension in chronic renal failure (CRF). Male Sprague-Dawley rats were five-sixths nephrectomized...
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Oxidative stress is associated with the number of components of metabolic syndrome: LIPGENE study

Yubero-Serrano EM, Delgado-Lista J, Pena-Orihuela P, Perez-Martinez P, Fuentes F, Marin C, Tunez I, Jose Tinahones F, Perez-Jimenez F, Roche HM, Lopez-Miranda J

  • KMID: 2154247
  • Exp Mol Med.
  • 2013 Jun;45(6):e28.
Previous evidence supports the important role that oxidative stress (OxS) plays in metabolic syndrome (MetS)-related manifestations. We determined the relationship between the number of MetS components and the degree of...
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Differentially-altered vascular guanylate cyclase isoforms in experimental hypertensive rats

Lee JU, Kang DG, Kook H, Kim IK, Oh BS

Pathophysiological implications of the vascular nitric oxide (NO)/cGMP pathway were investigated in various rat models of hypertension. The expression of brain and endothelial constitutive NO synthases (bNOS, ecNOS) was determined...
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The Effects of Antioxidants and Nitric Oxide Modulators on Hepatic Ischemic-Reperfusion Injury in Rats

Rhee JE, Jung SE, Shin SD, Suh GJ, Noh DY, Youn YK, Oh SK, Choe KJ

Ischemic-reperfusion injury (IRI) is thought to be caused by oxygen radicals. Nitric oxide (NO) also has been thought to play a key role in IRI. This experiment was designed to...
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