- Altered Vascular Expression of Nitric Oxide Synthase Isozymes in Hypertension
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Kim IK, Kang DG, Lee JE, Oh BS
- KMID: 1915496
- Korean J Thorac Cardiovasc Surg.
- 1999 Feb;32(2):138-143.
BACKGROUND: The endothelium-dependent vasorelaxation has been largely accounted for by the release of nitric oxide (NO). Three distinct isoforms of NO synthases (NOS) have been characterized, i.e., brain(bNOS), inducible (iNOS),... -
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- Altered renal nitric oxide system in experimental hypertensive rats
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Yang ES, Kang J, Lee DG
- KMID: 2285208
- Korean J Physiol Pharmacol.
- 1998 Aug;2(4):455-460.
The present study was aimed at investigating whether the development of hypertension is related with an altered expression of nitric oxide synthases (NOS) in the kidney. By Western blot analysis, the expression of... -
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- Management of Poisoning by Chemical Agents
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Hong YC
- KMID: 2347833
- J Korean Med Assoc.
- 2001 Dec;44(12):1336-1341.
- doi: 10.5124/jkma.2001.44.12.1336
Obtaining a complete and accurate history is one of the most crucial steps in the initial diagnosis and subsequent management of the poisoned patients. This information can then be integrated... -
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- Alcohol Withdrawal and Serum Nitrite Concentration
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Lee BC, Son HG, Choi IG
- KMID: 2334642
- J Korean Soc Biol Psychiatry.
- 2004 Jun;11(1):33-39.
OBJECTIVE: Nitric oxide(NO) has been known to be associated with tolerance and preference to alcohol. It has also been known to affect various alcohol drinking behavior, alcohol withdrawal symptoms and... -
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- Prevalence and Clinical Characteristics of Asymptomatic Pyuria in Chronic Kidney Disease
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Kwon YE, Oh DJ, Kim MJ, Choi HM
- KMID: 2466017
- Ann Lab Med.
- 2020 May;40(3):238-244.
- doi: 10.3343/alm.2020.40.3.238
BACKGROUND: Pyuria seems to be common in chronic kidney disease (CKD), irrespective of urinary tract infection (UTI). It has been hypothesized that sterile pyuria occurs in CKD because of chronic... -
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- Manganese Cytotoxicity Mediated by Potentiation of Nitric Oxide Production in Activated Glial Cell
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Kim SJ, Suh JY, Bae JH, Chung IS, Lee MY, Shin DH
- KMID: 1517672
- Korean J Aerosp Environ Med.
- 2003 Dec;13(4):190-197.
BACKGROUND: Glial cells are generally known to support normal neuronal functions tightly regulating the extracellular environment and providing energy substrates such as glucose. Therefore, dysfunction or loss of glial cells... -
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- Comparison between Immunostimulatory Activity and Molecular Structure of Different Polysaccharides
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Shim JY, Jung IS, Kim CW, Yun YS, Song JY
- KMID: 1637948
- Immune Netw.
- 2004 Jun;4(2):94-99.
- doi: 10.4110/in.2004.4.2.94
BACKGROUND: We previously reported that ginsan, a polysaccharide extracted from Panax ginseng had an immunostimulatory activity such as mitogenic activity, activation of macrophages and killer cells, and production of a... -
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- Decreased nitric oxide synthesis in rats with chronic renal failure
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Kim SW, Lee JU, Paek YW, Kang DG, Choi KC
- KMID: 1730639
- J Korean Med Sci.
- 2000 Aug;15(4):425-430.
- doi: 10.3346/jkms.2000.15.4.425
The present study was aimed at investigating whether an altered role of nitric oxide (NO) is involved in chronic renal failure (CRF). Rats were subjected to 5/6 nephrectomy and kept... -
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- Altered renal expression of nitric oxide synthase isozymes in spontaneously hypertensive rats
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Kim SW, Moon KH, Lee SC, Kim NH, Kang DG, Lee JU, Choi KC, Kang YJ
- KMID: 759080
- Korean J Intern Med.
- 1999 Jan;14(1):21-26.
OBJECTIVES: The present study was aimed at exploring whether the pathogenesis of hypertension is related with an altered expression of nitric oxide synthase (NOS) isozymes, i.e., bNOS, iNOS... -
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- Correlation of the Serum Nitrate/Nitrite Level with the Severity of Biliary Tract Inflammation
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Choi KH, Kim HS, Choi YS, Cho EH, Ahn SI, Lee KY, Hong KC, Choi SK, Hur YS, Kim SJ, Woo ZH, Shin SH, Cha SH, Cha YN
- KMID: 1844199
- J Korean Surg Soc.
- 2004 Jul;67(1):55-59.
PURPOSE: The relationship between the biophysical and biochemical processes of gallbladder bile and nitric oxide is still not well known. In this study, the correlation between nitric oxide production and... -
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- Erythropoietin does not affect nitric oxide system in rats with chronic renal failure
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Kim SW, Lee JU, Kang DG, Jung K, Kim NH, Suh SP, Choi KC, Kang YJ
- KMID: 648121
- J Korean Med Sci.
- 2000 Apr;15(2):183-188.
- doi: 10.3346/jkms.2000.15.2.183
We investigated to see whether an altered role of nitric oxide (NO) system is involved in erythropoietin (EPO)-induced hypertension in chronic renal failure (CRF). Male Sprague-Dawley rats were five-sixths nephrectomized... -
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- Tyrosine nitration site specificity identified by LC/MS in nitrite-modified collagen type IV
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Wang Z, Paik DC, Dillon JP, Gaillard E
- KMID: 1103683
- Exp Mol Med.
- 2007 Feb;39(1):74-83.
Non-enzymatic nitrite induced collagen cross-linking results in changes reminiscent of age-related damage and parallels the well-known model system, non-enzymatic glycation. We have recently observed that nitrite modification of basement membrane... -
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- Oxidative stress is associated with the number of components of metabolic syndrome: LIPGENE study
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Yubero-Serrano EM, Delgado-Lista J, Pena-Orihuela P, Perez-Martinez P, Fuentes F, Marin C, Tunez I, Jose Tinahones F, Perez-Jimenez F, Roche HM, Lopez-Miranda J
- KMID: 2154247
- Exp Mol Med.
- 2013 Jun;45(6):e28.
Previous evidence supports the important role that oxidative stress (OxS) plays in metabolic syndrome (MetS)-related manifestations. We determined the relationship between the number of MetS components and the degree of... -
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- Nitric Oxide Metabolites, Eosinophils and Eosinophilic Cationic Protein in Patients with Asthma: Sputum versus Blood
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Jang AS, Yeum CH, Choi IS
- KMID: 648898
- J Korean Med Sci.
- 2003 Aug;18(4):489-493.
- doi: 10.3346/jkms.2003.18.4.489
The monitoring of airway inflammation has assessed in bronchial asthma directly by sputum examination, and indirectly by measurements in peripheral blood. To investigate the diagnostic value of these two methods,... -
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- Epigallocatechin gallate, a constituent of green tea, suppresses cytokine-induced pancreatic beta-cell damage
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Han MK
- KMID: 1097262
- Exp Mol Med.
- 2003 Apr;35(2):136-139.
Cytokines produced by immune cells infiltrating pancreatic islets have been implicated as one of the important mediators of beta-cell destruction in insulin-dependent diabetes mellitus. In this study, the protective effects... -
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- Differentially-altered vascular guanylate cyclase isoforms in experimental hypertensive rats
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Lee JU, Kang DG, Kook H, Kim IK, Oh BS
- KMID: 1731311
- J Korean Med Sci.
- 1999 Aug;14(4):386-392.
- doi: 10.3346/jkms.1999.14.4.386
Pathophysiological implications of the vascular nitric oxide (NO)/cGMP pathway were investigated in various rat models of hypertension. The expression of brain and endothelial constitutive NO synthases (bNOS, ecNOS) was determined... -
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- The Relationship between Gastric Juice Nitrate/Nitrite Concentrations and Gastric Mucosal Surface pH
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Lee HK, Kim H, Kim HK, Cho YS, Kim BW, Han SW, Maeng LS, Chae HS, Kim HN
- KMID: 1414258
- Yonsei Med J.
- 2012 Nov;53(6):1154-1158.
- doi: 10.3349/ymj.2012.53.6.1154
PURPOSE: To investigate gastric juice nitrate/nitrite concentration according to mucosal surface pH extent (area) of gastric corpus intimately contacting the gastric juice. MATERIALS AND METHODS: We included ninety-nine patients with dyspepsia.... -
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- Effects of L-NAME, a non-specific nitric oxide synthase inhibitor, on AlCl3-induced toxicity in the rat forebrain cortex
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Stevanovic ID, Jovanovic , Jelenkovic A, Colic M, Stojanovic I, Ninkovic M
- KMID: 1089341
- J Vet Sci.
- 2009 Mar;10(1):15-22.
- doi: 10.4142/jvs.2009.10.1.15
The present experiments were done to determine the effectiveness of a non-specific nitric oxide synthase inhibitor, N-nitro-L-arginine methyl ester (L-NAME), on oxidative stress parameters induced by aluminium chloride (AlCl3) intrahippocampal... -
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- Piceatannol-3'-O-beta-D-glucopyranoside as an active component of rhubarb activates endothelial nitric oxide synthase through inhibition of arginase activity
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Woo A, Min B, Ryoo S
- KMID: 1104212
- Exp Mol Med.
- 2010 Jul;42(7):524-532.
- doi: 10.3858/emm.2010.42.7.053
Arginase competitively inhibits nitric oxide synthase (NOS) via use of the common substrate L-arginine. Arginase II has recently reported as a novel therapeutic target for the treatment of cardiovascular diseases... -
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- The Effects of Antioxidants and Nitric Oxide Modulators on Hepatic Ischemic-Reperfusion Injury in Rats
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Rhee JE, Jung SE, Shin SD, Suh GJ, Noh DY, Youn YK, Oh SK, Choe KJ
- KMID: 1109759
- J Korean Med Sci.
- 2002 Aug;17(4):502-506.
- doi: 10.3346/jkms.2002.17.4.502
Ischemic-reperfusion injury (IRI) is thought to be caused by oxygen radicals. Nitric oxide (NO) also has been thought to play a key role in IRI. This experiment was designed to... -
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