- Decreased nitric oxide synthesis in rats with chronic renal failure
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Kim SW, Lee JU, Paek YW, Kang DG, Choi KC
- KMID: 1730639
- J Korean Med Sci.
- 2000 Aug;15(4):425-430.
- doi: 10.3346/jkms.2000.15.4.425
The present study was aimed at investigating whether an altered role of nitric oxide (NO) is involved in chronic renal failure (CRF). Rats were subjected to 5/6 nephrectomy and kept... -
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- The stimulatory effect of IL-1beta on the insulin secretion of rat pancreatic islet is not related with iNOS pathway
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Jeong IK, Oh SH, Chung JH, Min YK, Lee MS, Lee MK, Kim KW
- KMID: 1093592
- Exp Mol Med.
- 2002 Mar;34(1):12-17.
Interleukin 1 (IL-1) is a pleiotropic cytokine with the potential to destroy pancreatic beta-cells, and thought to be involved in the pathogenesis of type I diabetes mellitus. Expression of inducible... -
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- Fasting-induced Down-regulation of NADPH-diaphorase in the Magnocellular PVN of Rats
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Lee JY, Kang DW, Kim DG, Jahng JW
- KMID: 1103916
- Yonsei Med J.
- 2004 Oct;45(5):917-922.
- doi: 10.3349/ymj.2004.45.5.917
In this study, we examined if glucocorticoids are required for the fasting-induced decrease of neuronal nitric oxide synthase (nNOS) in the magnocellular division of the paraventricular nucleus (PVN). Rats were... -
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- Aging affects the association between endothelial nitric oxide synthase gene polymorphism and acute myocardial infarction in the Korean male population
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Park JE, Hwang TH, Chu JA, Kim S, Choi YH, Lee SH, Seo JD, Lee WR, Lee WH
- KMID: 759492
- Korean J Intern Med.
- 2000 Jan;15(1):65-70.
OBJECTIVES: The aging process affects responsiveness and other functions of endothelium and vascular smooth muscle cells, predisposing the old vessels to the development of atherosclerotic lesions. Endothelial nitric oxide synthase ... -
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- Soluble factor from tumor cells induces heme oxygenase-1 by a nitric oxide-independent mechanism in murine peritoneal macrophages
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Kim SW, Oh HM, Kim BS, Chung HT, Han WC, Kim EC, Kim TH, Seo GS, Lyou JH, Nah YH, Jung JC, Choi SC, Jun CD
- KMID: 1088658
- Exp Mol Med.
- 2003 Feb;35(1):53-59.
Tumor target-derived soluble secretary factor has been known to influence macrophage activation to induce nitric oxide (NO) production. Since heme oxigenase-1 (HO-1) is induced by a variety of conditions associated... -
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- Protein kinase A mediates microglial activation induced by plasminogen and gangliosides
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Min KJ, Yang MS, Jou I, Joe EH
- KMID: 1123767
- Exp Mol Med.
- 2004 Oct;36(5):461-467.
In the injured brain, microglia is known to be activated and produce proinflammatory mediators such as interleukin-1beta (IL-1beta), tumor necrosis factor-alpha (TNF-alpha) and inducible nitric oxide synthase (iNOS). We investigated... -
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