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Induction of hepatic inducible nitric oxide synthase by cholesterol in vivo and in vitro

Kim JW, Kang KW, Oh GT, Song J, Kim ND, Pak YK

  • KMID: 1081463
  • Exp Mol Med.
  • 2002 May;34(2):137-144.
Cholesterol-rich diet impairs endothelial NO synthase (eNOS) and enhances inducible NOS (iNOS) expression. In this study, we investigated effects of cholesterol on iNOS expression in high-fat-fed rat models, HepG2 and...
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Anti-leishmanial Effects of Trinitroglycerin in BALB/C Mice Infected with Leishmania major via Nitric Oxide Pathway

Nahrevanian H, Najafzadeh M, Hajihosseini R, Nazem H, Farahmand , Zamani Z

This study investigated whether trinitroglycerine (TNG) as nitric oxide (NO) releasing agent had anti-leishmanial effects and mediated pathology in BALB/c mice infected with Leishmania major. Cutaneous leishmaniasis (CL), a zoonotic...
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