- Effects of Cl- channel blockers on the cardiac ATP-sensitive K+ channel
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Kwak YG
- KMID: 2285224
- Korean J Physiol Pharmacol.
- 1999 Jun;3(3):305-313.
To explore whether Cl- channel blockers interact with the ATP-sensitive K+ (KATP) channel, I have examined the effect of two common Cl- channel blockers on the KATP channel activity in isolated rat... -
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- Helicobacter pylori Vacuolating Toxin Exhibits Polar Activity of Cl Secretion and Secretory Response to Carbachol in T84 Cells
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Jin NG, Jin YR, So I, Kim KW
- KMID: 1611434
- Korean J Physiol Pharmacol.
- 2004 Oct;8(5):289-293.
To investigate whether VacA (vacuolating toxin) produced by Helicobacter pylori Korean stain 99 induces intestinal secretion, purified VacA was added to T84 cell monolayers mounted in Ussing chambers, and electrical... -
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- Effects of ATP on Pacemaker Activity of Interstitial Cells of Cajal from the Mouse Small Intestine
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Park IK, Kim JH, Park CG, Kim MY, Parajuli S, Hong CS, Choi S, Jun JY
- KMID: 2458587
- Chonnam Med J.
- 2018 Jan;54(1):63-71.
- doi: 10.4068/cmj.2018.54.1.63
Purinergic receptors play an important role in regulating gastrointestinal (GI) motility. Interstitial cells of Cajal (ICCs) are pacemaker cells that regulate GI smooth muscle activity. We studied the functional roles... -
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- Effects of K+ channel modulators on extracellular K+ accumulation during ischemia in the rat hippocampal slice
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Choi JK, Chun BG, Ryu PD
- KMID: 2285186
- Korean J Physiol Pharmacol.
- 1997 Dec;1(6):681-690.
Loss of synaptic transmission and accumulation of extracellular K+((K+)o) are the key features in ischemic brain damage. Here, we examined the effects of several K+ channel modulators on the early ischemic changes in... -
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- Neuronal Excitatory Action of GABA on the Pelvic Ganglia
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Gill SB, Cha SK, Kim DR, Jang SG, Jang YK, Kong ID
- KMID: 1822221
- J Korean Neurosurg Soc.
- 2004 Aug;36(2):145-149.
OBJECTIVE: In the central nervous system, gamma-aminobutyric acid (GABA) is well known to act as an inhibitory neurotransmitter by hyperpolarizing postsynaptic neurons through gating GABA-activated Cl- channels. To date, however,... -
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- Properties of spontaneous activity in gastric smooth muscle
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Suzuki H, Yamamoto Y, Hirst G
- KMID: 1554124
- Korean J Physiol Pharmacol.
- 1999 Apr;3(2):119-125.
Mammalian gastric smooth muscles generate spontaneous rhythmic contractions which are associated with slow oscillatory potentials (slow waves) and spike potentials. Spike potentials are blocked by organic Ca2+-antagonists, indicating that these result from the activation... -
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- Uridine-5'-Triphosphate Stimulates Chloride Secretion via Cystic Fibrosis Transmembrane Conductance Regulator and Ca2+-Activated Chloride Channels in Cultured Human Middle Ear Epithelial Cells
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Son EJ, Gee HY, Lee MG, Lee WS, Choi JY
- KMID: 2277285
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2011 Dec;54(12):840-846.
- doi: 10.3342/kjorl-hns.2011.54.12.840
BACKGROUND AND OBJECTIVES: Nucleotide binding to purinergic P2Y receptors contributes to the regulation of fluid and ion transport in the middle ear epithelial cells. Here, we investigated the regulatory mechanism... -
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- Screening study for genetic polymorphisms affecting pharmacokinetics of talniflumate
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Jin LH, Kim BH, Lee JH, Lee K, Kwack K, Yim SV
- KMID: 2406997
- Transl Clin Pharmacol.
- 2017 Dec;25(4):166-172.
- doi: 10.12793/tcp.2017.25.4.166
Talniflumate is a phthalidyl ester of niflumic acid, which has potent analgesic and anti-inflammatory effects and is widely used to treat inflammatory disorders, such as rheumatoid arthritis. To screen the... -
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