Next-generation sequencing is widely used to detect a variety of genetic defects in many disorders. The detection of somatic variants in patients with cancer, including hematologic malignancy, is important for...

Germline predisposition (GPD) to hematological malignancies has gained interest because of the increased use of genetic testing in this field. Recent studies have suggested that GPD is underrecognized and requires appropriate genomic testing for an accurate diagnosis. Identification of GPD significantly affects...