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Nucleotide Binding Oligomerization Domain 1 Is an Essential Signal Transducer in Human Epithelial Cells Infected with Helicobacter pylori That Induces the Transepithelial Migration of Neutrophils

Kim BJ, Kim JY, Hwang ES, Kim JG

BACKGROUND/AIMS: The cytosolic host protein nucleotide binding oligomerization domain 1 (Nod1) has emerged as a key pathogen recognition molecule for innate immune responses in epithelial cells. The purpose of the...
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In vitro Model System of Transepithelial Migration of Neutrophil by Helicobacter pylori

Jung HC, Kim JG, Kim JM, Song IS, Park SM

  • KMID: 772517
  • Korean J Gastroenterol.
  • 2003 Jul;42(1):20-26.
BACKGROUND/AIMS: Migration of neutrophil across the intestinal epithelium is a structural hallmark of active intestinal diseases. One of the characteristic histologic features of Helicobacter pylori (H. pylori) infection is...
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Possible roles of LFA-1 and Fc gamma receptors on the functional immaturities of cord blood polymorphonuclear leukocytes

Kim NA, Choi IH, Shin JS, Park SK, Kim NS, Choi DH, Kim SJ

The functional immaturity of PMNs is one of the major causes of overwhelming sepsis in newborns. In this study, we observed functions and surface markers of PMNs to investigate what...
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