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The effects of monokines on neutrophil activation

Kim SY, Kang HS, Lee JS, Yoon SR, Lee CE, Pyun KH

  • KMID: 1690344
  • Korean J Immunol.
  • 1991 Nov;13(2):135-142.
No abstract available.
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Level of Plasma Elastase-α1- Proteinase Inhibitor in Patients with Behcet's Disease

Shin DJ, Lee SH, Kim DW, Jun JB, Chung SL, Kim JC

BACKGROUND: The common histopathology of Behget's disease is vasculitis associated with activation of neutrophils. The level of plasma elastase a 1 proteinase inhibitor (E a 1 PI), which represents the...
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Changes of serum neutrophil chemotactic activity(NCA) and myeloperoxidase(MPO) level following lysine-aspirin(L-ASA) bronchoprovocation test in aspirin-sensitive asthmatic patients

Kim SS, Kim HY, Nam DH, Jung KS, Park HS

  • KMID: 1907979
  • J Asthma Allergy Clin Immunol.
  • 1999 Apr;19(2):181-187.
BACKGROUND: There have been few reports suggesting involvement of mast cell and neutrophil to induce bronchoconstriction in aspirin-sensitive asthrna. OBJECTIVE: To evaluate mast cell and neutrophil activation in pathogenesis of...
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Evidence for neutrophil activation in induced sputum from patients with TDI - induced occupational asthma

Kim HY, Nahm DH, Park HS

  • KMID: 2286134
  • J Asthma Allergy Clin Immunol.
  • 1998 Sep;18(3):441-450.
BACKGROUND: Toluene diisocyanate (TDI) is the most prevalent agent to cause occupational asthma (OA) in Korea. The pathogenic mechanism of TDI-induced OA is still unclear. Involvement of both immunological and non-immunologicaI mechanisms...
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Usefulness of circulating vascular endothelial growth factor and neutrophil elastase as diagnostic markers of disseminated intravascular coagulation in non-cancer patients

Joo SY, Kim JE, Kim JY, Han KS, Kim HK

BACKGROUND: Disseminated intravascular coagulation (DIC) is characterized by platelet and neutrophil activation. Platelets are the major source of circulating vascular endothelial growth factor (VEGF). Endostatin, an anti-angiogenic factor, is a...
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High Glucose and/or Free Fatty Acid Damage Vascular Endothelial Cells via Stimulating of NAD(P)H Oxidase-induced Superoxide Production from Neutrophils

Kim SS, Kim SY, Lee SH, Kang YH, Kim IJ, Kim YK, Son SM

BACKGROUND: Oxidative stress and inflammation are important factors in the pathogenesis of diabetes and contribute to the development of diabetic complications. To understand the mechanisms that cause vascular complications in...
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Study on Role of Neutrophil in Endothelial Cell Injury under High Glucose Condition

Son SM, Kim IJ, Kim YK

  • KMID: 1767981
  • J Korean Diabetes Assoc.
  • 2000 Dec;24(6):652-665.
BACKGROUND: High glucose level plays a major role in the injury of endothelium during the early event in diabetic vascular complication. It was speculated that high glucose level may cause...
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Urinary trypsin inhibitor attenuates lipopolysaccharide-induced neutrophil activation

Lee SH, Kim HJ, Han HJ, Li M, Kwak SH, Park S

BACKGROUND: Urinary trypsin inhibitor (UTI), which is speculated to have anti-inflammatory effects, is one of serine protease inhibitors found in human urine and blood. The present study was conducted to...
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Effect of Rebamipide on the Neutrophils Activated by Helicobacter pylori Water-Soluble Proteins

Kim JS, Kim JM, Kim BG, Kim SG, Kim JW, Kim CG, Jung HC, Song IS

  • KMID: 1606493
  • Korean J Gastroenterol.
  • 2002 Jan;39(1):13-21.
Background/Aims: Helicobacter pylori (H. pylori) infection induces persistent neutrophil infiltration in gastric mucosa. The expression of cyclooxygenase (COX)-2 and inhibition of apoptosis in the neutrophils could contribute to the pathogenesis...
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Angiostatin Works as Immune Modulatory Molecules via Inhibition of Neutrophil Activation and Migration

Woo SY

Angiostatin is derived from enzymatic degradation of plasminogen and it has endogenous anti-angiogenic properties. Although tumor cells, macrophages, platelets, and neutrophils generate high amount of angiostatin, its expression is increased...
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Changes of Serum Neopterin and Elastase - alpha1 - Antitrypsin

Kim HJ, Chung SL, Kim JC, Kim MK

  • KMID: 2085728
  • Korean J Dermatol.
  • 1994 Aug;32(4):547-553.
BACKGROUND: Generalized immune aetivation occurs early in the course of many infectious diseases. Clinical investigations have known that immune activation can be qiantified by the measurement of soluble immune activation...
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The Effects of Activated Nasal Polyp Epithelial Cells by Fungi on Activation and Migration of Neutrophils

Kim JK, Shin SH, Kim YD

  • KMID: 2276465
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Aug;48(8):1014-1019.
BACKGROUND AND OBJECTIVES: Sinusitis is one of the most common chronic disease in otolaryngology but it's pathogenesis is not well understood. Fungi are known to induce the production of chemical...
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Effect of C1 esterase inhibitor on the cardiac dysfunction following ischemia and reperfusion in the isolated perfused rat heart

Lee GY, Shin YK, Jang YY, Song JH, Kim DJ

  • KMID: 2071561
  • Korean J Physiol Pharmacol.
  • 1999 Dec;3(6):579-586.
Complement-mediated neutrophil activation has been hypothesized to be an important mechanism of reperfusion injury. It has been proposed that C1 esterase inhibitor (C1 INH) may prevent the complement-dependent activation of polymorphonuclear leukocytes (PMNs)...
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Evaluation of Neutrophil Activation Status According to the Phenotypes of Adult Asthma

Kim SH, Uuganbayar U, Trinh HK, Pham D, Kim N, Kim M, Sohn H, Park HS

PURPOSE: Neutrophils are considered key effector cells in the pathogenic mechanisms of airway inflammation in asthma. This study assessed the activation status of neutrophils in adult asthmatics, and the therapeutic...
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Molecular Mechanisms of Neutrophil Activation in Acute Lung Injury

Yum HK

ABBREVIATIONS: Akt/PKB protein kinase B, ALI acute lung injury, ARDS acute respiratory distress syndrome, CREB C-AMP response element binding protein, ERK extracelluar signal-related kinase, fMLP fMet-Leu-Phe, G-CSF granulocyte colony-stimulating factor,...
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The Effects of Flecainide Acetate on Inflammatory-Immune Response in Lipopolysaccharide-Stimulated Neutrophils and on Mortality in Septic Rats

Chung SY, Kim J, Bae HB, Tin TD, Ju W, Kwak SH

BACKGROUND: Flecainide acetate is a drug used primarily for cardiac arrhythmia. Some studies also imply that flecainide acetate has the potential to regulate inflammatory-immune responses; however, its mechanism of action...
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Anti-inflammatory Effects of Flavonoids on TNBS-induced Colitis of Rats

Joo M, Kim HS, Kwon TH, Palikhe A, Zaw TS, Jeong JH, Sohn UD

It has been shown that the extracts including eupatilin and quercetin-3-beta-D-glucuronopyranoside had mucoprotective effects on the esophagus and stomach through their antioxidant activities. This study was designed to investigate the...
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Effects of Hyaluronic Acid on the Polymorphonuclear Leukocyte (PMN) Release of Active Oxygen and Protection of Bovine Corneal Endothelial Cells from Activated PMNs

Lym HS, Suh Y, Park CK

The goal of this study was to evaluate the function of hyaluronic acid (HA) on the active oxygen release from polymorphonuclear leukocytes (PMNs) and the protective effect of bovine corneal...
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