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From the Editor-in-Chief: Featured Articles in the June 2024 Issue

Han I

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Commentary on “The Utility and Feasibility of Smart Glasses in Spine Surgery: Minimizing Radiation Exposure During Percutaneous Pedicle Screw Insertion”

Liawrungrueang W

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Commentary on “Comparison of the Clinical Efficacy of Anabolic Agents and Bisphosphonates in the Patients With Osteoporotic Vertebral Fracture: Systematic Review and Meta-analysis of Randomized Controlled Trials”

Cho DC

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Commentary on “Radiological and Clinical Significance of Cervical Dynamic Magnetic Resonance Imaging for Cervical Spondylotic Myelopathy”

Apaydin AS, Than K

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Commentary on “Baseline Frailty Measured by the Risk Analysis Index and 30-Day Mortality After Surgery for Spinal Malignancy: Analysis of a Prospective Registry (2011–2020)”

Tsuang FY

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Neuroprotection and Neuroregeneration of the Injured Spinal Cord: A Focus on Degenerative Cervical Myelopathy – Commentary on “Pharmacological Treatment of Degenerative Cervical Myelopathy: A Critical Review of Current Evidence”

Pedro KM, Fehlings MG

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Erratum: Exploring lncRNA Expression Patterns in Patients With Hypertrophied Ligamentum Flavum

Chen J, Zhong G, Qiu M, Ke W, Xue J, Chen J

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Comparative Review of the Socioeconomic Burden of Lower Back Pain in the United States and Globally

Chang D, Lui A, Matsoyan A, Safaee M, Aryan H, Ames C

Internationally, the United States (U.S.) cites the highest cost burden of low back pain (LBP). The cost continues to rise, faster than the rate of inflation and overall growth of...
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Knockdown of best1 Gene in Zebrafish Caused Abnormal Neuronal and Skeletal Development - A Subtype of Craniovertebral Junction Malformation?

Liu Z, Li K, Wang K, Zhang L, Jia S, Wang H, Jian F, Wu H

Objective: To investigate the developmental defects caused by knockdown of best1 gene in zebrafish as a model for a subtype of craniovertebral junction (CVJ) malformation. Methods: Two antisense morpholinos (MOs) were...
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Finite Element Analysis of Stress Distribution and Range of Motion in Discogenic Back Pain

Cho PG, Yoon SJ, Shin DA, Chang MC

Objective: Precise knowledge regarding the mechanical stress applied to the intervertebral disc following each individual spine motion enables physicians and patients to understand how people with discogenic back pain should...
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Comparison of Single or Double Titanium Mesh Cage for Anterior Reconstruction After Total En Bloc Spondylectomy for Thoracic and Lumbar Spinal Tumors

Leng A, Wang Q, Li J, Long Y, Shi S, Meng L, Guo M, Yu H, Xiang L

Objective: To compare the clinical efficacy of anterior column reconstruction using single or double titanium mesh cage (TMC) after total en bloc spondylectomy (TES) of thoracic and lumbar spinal tumors. Methods:...
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The Utility and Feasibility of Smart Glasses in Spine Surgery: Minimizing Radiation Exposure During Percutaneous Pedicle Screw Insertion

Hiranaka Y, Takeoka Y, Yurube T, Tsujimoto T, Kanda Y, Miyazaki K, Ohnishi H, Matsuo T, Ryu M, Kumagai N, Kuroshima K, Kuroda R, Kakutani K

Objective: Spine surgeons are often at risk of radiation exposure due to intraoperative fluoroscopy, leading to health concerns such as carcinogenesis. This is due to the increasing use of percutaneous...
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Preliminary Clinical and Radiological Outcomes of the “No-Punch” Decompression Techniques for Unilateral Biportal Endoscopic Spine Surgery

Pao JL

Objective: To avoid the most offending surgical instrument for dural tears, we develop a “no-punch” decompression technique for unilateral biportal endoscopic (UBE) spine surgery. Methods: This retrospective study enrolled 68 consecutive...
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Are There Advantages in Cervical Intrafacetal Fusion With Minimal Posterolateral Fusion (PLF) Compared to Conventional PLF in Posterior Cervical Fusion?

Jang SW, Lee SH, Joo JK, Shin HK, Park JH, Roh SW, Jeon SR

Objective: We propose that cervical intrafacetal fusion (cIFF) using bone chip insertion into the facetal joint space additional to minimal PLF is a supplementary fusion method to conventional posterolateral fusion...
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A Nomogram for Predicting Overall Survival of Patients With Primary Spinal Cord Glioblastoma

Wang Y, Mu Q, Sheng M, Chen Y, Jian F, Li R

Objective: Primary spinal cord glioblastoma (PSCGBM) is a rare malignancy with a poor prognosis. To date, no prognostic nomogram for this rare disease was established. Hence, we aimed to develop...
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Inhibition of Ferroptosis by Mesenchymal Stem Cell-Derived Exosomes in Acute Spinal Cord Injury: Role of Nrf2/GCH1/BH4 Axis

Chen Y, Li B, Quan J, Li Z, Li Y, Tang Y

Objective: The therapeutic benefits of exosomes obtained from mesenchymal stem cells (MSCs) in acute spinal cord injury (SCI) have been demonstrated in recent years, but the precise mechanisms remain unknown....
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Comparison of Surgical Burden, Radiographic and Clinical Outcomes According to the Severity of Baseline Sagittal Imbalance in Adult Spinal Deformity Patients

Park SJ, Park JS, Kang DH, Kim HJ, Lim YM, Lee CS

Objective: To determine the clinical impact of the baseline sagittal imbalance severity in patients with adult spinal deformity (ASD). Methods: We retrospectively reviewed patients who underwent ≥ 5-level fusion including the...
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Artificial Intelligence in Spinal Imaging and Patient Care: A Review of Recent Advances

Lee S, Jung JY, Mahatthanatrakul A, Kim JS

Artificial intelligence (AI) is transforming spinal imaging and patient care through automated analysis and enhanced decision-making. This review presents a clinical task-based evaluation, highlighting the specific impact of AI techniques...
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Baseline Frailty Measured by the Risk Analysis Index and 30-Day Mortality After Surgery for Spinal Malignancy: Analysis of a Prospective Registry (2011–2020)

Thommen R, Bowers CA, Segura AC, Roy JM, Schmidt MH

Objective: To evaluate the prognostic utility of baseline frailty, measured by the Risk Analysis Index (RAI), for prediction of postoperative mortality among patients with spinal malignancy (SM) undergoing resection. Methods: SM...
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Predictors of Persistent Postoperative Numbness Following Lumbar Fusion in Patients Older Than 75 Years: A Minimum 2-Year Follow-up

Tsujimoto T, Kanayama M, Fukada S, Oha F, Shimamura Y, Hasegawa Y, Hashimoto T, Kakutani K, Yurube T, Takeoka Y, Miyazaki K, Iwasaki N

Objective: To evaluate the preoperative and perioperative predictors of persistent leg numbness following lumbar fusion in patients aged ≥ 75 years. Methods: This single-center retrospective study examined 304 patients aged ≥...
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