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From the Editor-in-Chief: Featured Articles in the June 2023 Issue

Han I

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Commentary on “Mini-Open Intercostal Retroperitoneal Approach for Upper Lumbar Spine Lateral Interbody Fusion”

Ropper AE

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Commentary on “Different Ways to Die: Cell Death Pathways and Their Association With Spinal Cord Injury”

Luo J, Stein JB, Lee KB

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To Be Trustworthy, the Robot Assisted Cervical Spine Surgery Needs More Than Accuracy Beyond Technological Limitations: Commentary on “Robotics in Cervical Spine Surgery: Feasibility and Safety of Posterior Screw Placement”

Yi S

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Commentary on “Perioperative Clinical Features and Long-term Prognosis After Oblique Lateral Interbody Fusion (OLIF), OLIF With Anterolateral Screw Fixation, or OLIF With Percutaneous Pedicle Fixation: A Comprehensive Treatment Strategy for Patients With Lumbar Degenerative Disease”

Ju CI

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The Reality of Benefit in Surgical Removal for Spinal Cord Cavernous Malformation: Commentary on “Acceptance of Early Surgery for Treatment of Spinal Cord Cavernous Malformation in Contemporary Japan”

Takahashi T, Kanematsu R

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Commentary on “Three-Dimensional-Printed Titanium Versus Polyetheretherketone Cages for Lumbar Interbody Fusion: A Systematic Review of Comparative In Vitro, Animal, and Human Studies”

Liu Y, Suvithayasiri S, Kim JS

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The Fine Line Between Simplicity and Oversimplification: Comparing the Risk Analysis Index and 5-Factor Modified Frailty Index as Frailty Assessment Tools

Owodunni OP, Uzoukwu C, Courville EN, Schmidt MH, Bowers CA

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Commentary on “The Role and Clinical Outcomes of Endoscopic Spine Surgery of Treating Spinal Metastases; Outcomes of 29 Cases From 8 Countries”

Liawrungrueang W, Kotheeranurak V

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From the Spinopelvic Parameters to Global Alignment and Proportion Scores in Adult Spinal Deformity

Cho Y, Jo DJ, Hyun SJ, Park JH, Yang NR

In the last 20 years, sagittal alignment and balance of the spine have become one of the most important issues in the field of spine surgery. Recent studies emphasize that...
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METTL3 Affects Spinal Cord Neuronal Apoptosis by Regulating Bcl-2 m6A Modifications After Spinal Cord Injury

Guo S, Lin T, Chen G, Shangguan Z, Zhou L, Chen Z, Shi T, Chen D, Wang Z, Liu W

Objective: Spinal cord injury (SCI) is a severe type of neurological trauma. N6-methyladenosine (m6A) modification is one of the most common internal modifications of RNA. The role of METTL3, the...
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Different Ways to Die: Cell Death Pathways and Their Association With Spinal Cord Injury

Guha L, Singh N, Kumar H

Cell death is a systematic/nonsystematic process of cessation of normal morphology and functional properties of the cell to replace and recycle old cells with new also promoting inflammation in some...
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Vertebral Body Sliding Osteotomy as a Surgical Strategy for the Treatment of Cervical Myelopathy: Complications and Pitfalls

Lee DH, Cho ST, Park S, Hwang CJ, Cho JH, Kim JH

Objective: This retrospective cohort study has been aimed at evaluating the incidence of complications after vertebral body sliding osteotomy (VBSO) and analyzing some cases. Furthermore, the complications of VBSO were...
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Acceptance of Early Surgery for Treatment of Spinal Cord Cavernous Malformation in Contemporary Japan

Kurokawa R, Endo T, Takami T, for the Investigators of Intramedullary Spinal Cord Tumors in the Neurospinal Society of Japan

Objective: Spinal cord cavernous malformation (CM) is an intramedullary vascular lesion that may present with progressive symptoms. Surgery is recommended for symptomatic patients, but optimal timing of surgery is debatable....
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Proteomic Comparison of Paraspinal Muscle Imbalance Between Idiopathic Scoliosis and Congenital Scoliosis

Wang Z, Huang X, Tan H, Liang J, Li Z, Shen J

Objective: This study aims to compare the proteomic profiles of paraspinal muscle imbalance between idiopathic scoliosis (IS) and congenital scoliosis (CS). Methods: Bilateral paraspinal muscles of 5 pairs of matched IS...
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Biomechanical Comparison of Multilevel Stand-Alone Lumbar Lateral Interbody Fusion With Posterior Pedicle Screws: An In Vitro Study

Mok JM, Lin Y, Tafur JC, Diaz RL, Amirouche F

Objective: Lumbar lateral interbody fusion (LLIF) allows placement of large interbody cages while preserving ligamentous structures important for stability. Multiple clinical and biomechanical studies have demonstrated the feasibility of stand-alone...
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Complication Rates and Utilization Trends of 3-Level Posterior Column Osteotomy Compared to Single-Level Pedicle Subtraction Osteotomy

Mills ES, Mertz K, Faye E, Bell JA, Ton AT, Wang JC, Alluri RK, Hah RJ

Objective: The objective of this study is to assess differences in complication profiles between 3-level posterior column osteotomy (PCO) and single-level pedicle subtraction osteotomy (PSO) as both are reported to...
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Detection of Glioma-Related Hotspot Mutations Through Sequencing of Cerebrospinal Fluid (CSF)-Derived Circulating Tumor DNA: A Pilot Study on CSF-Based Liquid Biopsy for Primary Spinal Cord Astrocytoma

Cheng L, Duan W, Guan J, Wang K, Liu Z, Wang X, Wang Z, Wu H, Chen Z, Jian F

Objective: Although cerebrospinal fluid (CSF)-based liquid biopsy was proved to be practical in molecular analysis of intracranial gliomas, liquid biopsy of primary intramedullary astrocytoma was rarely reported. Given the distinct...
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Perioperative Clinical Features and Long-term Prognosis After Oblique Lateral Interbody Fusion (OLIF), OLIF With Anterolateral Screw Fixation, or OLIF With Percutaneous Pedicle Fixation: A Comprehensive Treatment Strategy for Patients With Lumbar Degenerative Disease

Zhang X, Wang Y, Zhang W, Liu S, Liu Z, Wang K, Wu H

Objective: To compare the efficacy of oblique lateral interbody fusion (OLIF), OLIF combined with anterolateral screw fixation (OLIF-AF), and OLIF combined with percutaneous pedicle screw fixation (OLIF-PF) in the treatment...
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Global Research Trends of Exosomes in the Central Nervous System: A Bibliometric and Visualized Analysis

Zhuo Y, Ai K, He K, Wu B, Peng J, Xiang J, Zhang G, Jiao Z, Zhou R, Zhang H

Objective: Exosomes in the central nervous system (CNS) have become an attractive area of research with great value. However, few bibliometric analysis has been conducted. The study aimed to visualize...
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