- Effect of Neurosteroid Modulation on Global Ischaemia-Reperfusion-Induced Cerebral Injury in Mice
-
Grewal AK, Jaggi AS, Rana AC, Singh N
- KMID: 2285474
- Korean J Physiol Pharmacol.
- 2013 Dec;17(6):485-491.
- doi: 10.4196/kjpp.2013.17.6.485
The present study was designed to investigate the putative effect of neurosteroid modulation on global ischaemia-reperfusion-induced cerebral injury in mice. Bilateral carotid artery occlusion followed by reperfusion, produced a significant... -
- CITED
-
- Close
- SHARE
-
- Close
- Spinal Cord Injury and Related Clinical Trials
-
Kim YH, Ha KY, Kim SI
- KMID: 2412297
- Clin Orthop Surg.
- 2017 Mar;9(1):1-9.
- doi: 10.4055/cios.2017.9.1.1
Spinal cord injury (SCI) has been considered an incurable condition and it often causes devastating sequelae. In terms of the pathophysiology of SCI, reducing secondary damage is the key to... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of Iron-chelator on the Neurotoxicity Induced by Oxygen Radicals
-
Park ST
- KMID: 2376333
- Korean J Phys Anthropol.
- 1995 Dec;8(2):113-121.
- doi: 10.11637/kjpa.1995.8.2.113
In order to elucidate the neurotoxicity of oxygen radicals, neurotoxic effect was investigated after cultured mouse spinal sensory ganglionic cells were exposed to oxygen radicals which were generated enzymatically by... -
- CITED
-
- Close
- SHARE
-
- Close
- The Neuroprotective Effects of Woohwangcheongsim-won on Cerebral Ischemia following the Middle Cerebral Artery Occlusion in Rats
-
Park IS
- KMID: 2224473
- Korean J Anat.
- 2006 Jun;39(3):227-233.
The purpose of this study is to evaluate the effects of Woohwangcheongsim-won on reperfusion following the MCA occlusion in rats. To evaluate the effect of Woohwangcheongsim-won on reperfusion following the... -
- CITED
-
- Close
- SHARE
-
- Close
- Quantitative Analysis of Agmatine by HPLC in Ischemic Brain
-
Hong JS, Chun H, Jeong HS, Kim JH, Lee WT, Park KA, Lee JE
- KMID: 1610757
- Korean J Anat.
- 2003 Aug;36(4):257-264.
Agmatine, a widely distributed molecule in mammalian tissues, shows neuroprotective effects in brain ischemia. We describe the neuroprotective effects of agmatine in the mouse MCAO model and the quantitative change... -
- CITED
-
- Close
- SHARE
-
- Close
- The use of ketogenic diet in special situations: expanding use in intractable epilepsy and other neurologic disorders
-
Lee M
- KMID: 2284389
- Korean J Pediatr.
- 2012 Sep;55(9):316-321.
- doi: 10.3345/kjp.2012.55.9.316
The ketogenic diet has been widely used and proved to be effective for intractable epilepsy. Although the mechanisms underlying its anti-epileptic effects remain to be proven, there are increasing experimental... -
- CITED
-
- Close
- SHARE
-
- Close
- Neuroprotective Effects of Lithium on NMDA-induced Excitotoxicity in Mouse Cerebrum
-
Kwon GY, Kim SK
- KMID: 2285321
- Korean J Physiol Pharmacol.
- 2006 Jun;10(3):111-121.
Neuroprotective properties of lithium were evaluated by using in vivo NMDA excitotoxicity model. Systemic injection of NMDA to young mice induced neuronal apoptosis mediated by both TNFR-1 and Fas ligand,... -
- CITED
-
- Close
- SHARE
-
- Close
- Challenges and Pitfalls of Stroke Therapeutics Research
-
Jung KH
- KMID: 2288739
- Korean J Stroke.
- 2011 Apr;13(1):11-15.
Ischemia-reperfusion injury is complicated with multiple injury pathways. If a particular agent is used to restore blood flow and prevent cell death, many damaged neurons may come back to life.... -
- CITED
-
- Close
- SHARE
-
- Close
- Neuroprotective Effect of Duloxetine on Chronic Cerebral Hypoperfusion-Induced Hippocampal Neuronal Damage
-
Park JA, Lee CH
- KMID: 2429050
- Biomol Ther.
- 2018 Mar;26(2):115-120.
- doi: 10.4062/biomolther.2016.248
Chronic cerebral hypoperfusion (CCH), which is associated with onset of vascular dementia, causes cognitive impairment and neuropathological alterations in the brain. In the present study, we examined the neuroprotective effect... -
- CITED
-
- Close
- SHARE
-
- Close
- Protective Effect of Ginsenoside Rb1 and Rg1 Against beta Amyloid ( 25-35 )-Induced Neurotoxicity on B103 cells
-
Lee EA, Joo IS, Huh K, Mook IH
- KMID: 2066182
- J Korean Neurol Assoc.
- 1999 Sep;17(5):688-693.
BACKGROUND: Ginseng extracts, known to enhance bodily functions including learning and memory, were reported to have in vitro neuroprotective activity in vitro. Here We demonstrate the possible therapeutic effects of... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of Allopurinol on Methylmercuric Chloride in Cultured O1igodendrocytes
-
Park ST, Park BR, Chung YT
- KMID: 2376318
- Korean J Phys Anthropol.
- 1996 Dec;9(2):183-188.
- doi: 10.11637/kjpa.1996.9.2.183
To elucidate the neurotoxic mechanism of methylmercury on cultured bovine oligodendrocytes, neurotoxic effect was estimated by MTT assay after cultures were exposed to various concentrations of methylmercuric chloride (MMC). In... -
- CITED
-
- Close
- SHARE
-
- Close
- The Neuroprotective and Neurotrophic Effects of Tremella fuciformis in PC12h Cells
-
Park KJ, Lee SY, Kim HS, Yamazaki M, Chiba K, Ha HC
- KMID: 2312505
- Mycobiology.
- 2007 Mar;35(1):11-15.
We examined the neuroprotective and neurotrophic effects of Tremella fuciformis. The neurotrophic effects of the hot water extract of T. fuciformis was evaluated by microscopically monitoring its potency to induce... -
- CITED
-
- Close
- SHARE
-
- Close
- Neuroprotective Effect of Fucoidan against N-methyl-D-aspartate-Induced Excitotoxicity in Rat Hippocampus
-
Ha YJ, Kim YS, Lee HJ, Seo JH, Sung YH, Kim SE, Shin MS, Kim CJ
- KMID: 2165304
- Exp Neurobiol.
- 2009 Dec;18(2):123-128.
- doi: 10.5607/en.2009.18.2.123
Fucoidan, a sulfated polyanionic polymer of L-fucose, is obtained from brown marine macroalgae. In the present study, neuroprotective effect of fucoidan against N-methyl- D-aspartate (NMDA)-induced excitotoxicity in the hippocampus was... -
- CITED
-
- Close
- SHARE
-
- Close
- Neuroprotective Effect of Genistein Against beta Amyloid-Induced Neurotoxicity
-
Bang OY, Mook IH, Huh K
- KMID: 2343041
- J Korean Neurol Assoc.
- 2003 Apr;21(2):174-182.
BACKGROUND: Estrogen is beneficial to patients with Alzheimer's disease but has a limited clinical use due to its proliferative and oncogenic effects on non-neuronal estrogen responsive cells. METHODS: In an... -
- CITED
-
- Close
- SHARE
-
- Close
- Neuroprotective Effect of Growth Hormone in Neonatal Rat with Hypoxic Ischemic Brain Injury
-
Yu JH, Song KS, Ann RZ
- KMID: 2144622
- J Korean Soc Pediatr Endocrinol.
- 2001 Dec;6(2):147-153.
PURPOSE: To investigate the neuroprotective effect of growth hormone(GH) on neuronal cell necrosis and apoptosis at 1 week and 3 weeks after hypoxic ischemic brain injury. METHODS: Sprague-Dawley rats, seven-day-old,... -
- CITED
-
- Close
- SHARE
-
- Close
- Neuroprotective Effect of Estrogen on Motor Neuron Cells Expressing Wild Type or Mutant Cu/Zn Superoxide Dismutase
-
Kim HJ, Park SH, Kim MH, Kim HJ, Lee KW
- KMID: 2343020
- J Korean Neurol Assoc.
- 2002 Sep;20(5):525-529.
BACKGROUND: Recently, the mechanism involved in nitric oxide (NO)-mediated motor neuron death is under extensive investigation. The role of Cu/Zn superoxide dismutase (SOD) mutation, which is found in about 2%... -
- CITED
-
- Close
- SHARE
-
- Close
- Neurotoxic Effect of Streptozotocin and Neuroprotective Effect of Insulin Growth Factor-II to the Cultured Mouse Schwann Cells
-
Jang CH, Park ST
- KMID: 2012698
- Korean J Otolaryngol-Head Neck Surg.
- 2000 Jun;43(6):577-581.
BACKGROUND: The sensorineural hearing loss due to diabetes is progressive and bilateral, and predominantly occurs in the old, although its accurate pathogenesis is still unknown. Objectives: The purpose of this... -
- CITED
-
- Close
- SHARE
-
- Close
- The Neuroprotective Effect of Intravitreal Melatonin Injection in Pressure-induced Retinal Ischemia
-
Lee SJ, Son WS, Kwak HW
- KMID: 2125071
- J Korean Ophthalmol Soc.
- 2001 Apr;42(4):638-646.
PURPOSE: The authors sought to determine the neuroprotective effect of melatonin in a model of ischemic injury in rabbit retina. METHODS: Ischemia was induced by high intraocualr pressure. A dose... -
- CITED
-
- Close
- SHARE
-
- Close
- TLR5 Activation through NF-κB Is a Neuroprotective Mechanism of Postconditioning after Cerebral Ischemia in Mice
-
Jeong J, Kim S, Lim DS, Kim SH, Doh H, Kim SD, Song YS
- KMID: 2389008
- Exp Neurobiol.
- 2017 Aug;26(4):213-226.
- doi: 10.5607/en.2017.26.4.213
Postconditioning has been shown to protect the mouse brain from ischemic injury. However, the neuroprotective mechanisms of postconditioning remain elusive. We have found that toll-like receptor 5 (TLR5) plays an... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of Pioglitazone on Excitotoxic Neuronal Damage in the Mouse Hippocampus
-
Lee CH, Yi MH, Chae DJ, Zhang E, Oh SH, Kim DW
- KMID: 2380336
- Biomol Ther.
- 2015 May;23(3):261-267.
- doi: 10.4062/biomolther.2014.146
Pioglitazone (PGZ), a synthetic peroxisome proliferator-activated receptor gamma agonist, is known to regulate inflammatory process and to have neuroprotective effects against neurological disorders. In the present study, we examined the... -
- CITED
-
- Close
- SHARE
-
- Close
