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A priming role of local estrogen on exogenous estrogen-mediated synaptic plasticity and neuroprotection

Chamniansawat S, Chongthammakun S

  • KMID: 1383803
  • Exp Mol Med.
  • 2012 Jun;44(6):403-411.
The localization of estrogen (E2) has been clearly shown in hippocampus, called local hippocampal E2. It enhanced neuronal synaptic plasticity and protected neuron form cerebral ischemia, similar to those effects...
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Granulocyte Stimulating Factor Attenuates Hypoxic-ischemic Brain Injury by Inhibiting Apoptosis in Neonatal Rats

Kim BR, Shim JW, Sung DK, Kim SS, Jeon GW, Kim MJ, Chang YS, Park WS, Choi ES

PURPOSE: This study was undertaken to determine the neuroprotective effect of granulocyte stimulating factor (G-CSF) on neonatal hypoxic-ischemic brain injury. MATERIALS AND METHODS: Seven-day-old male newborn rat pups were subjected...
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Neuroprotective Effect of Ginseng Total Saponins in Experimental Traumatic Brain Injury

Ji YC, Kim YB, Park SW, Hwang SN, Min BK, Hong HJ, Kwon JT, Suk JS

In the present study, we investigated whether ginseng total saponins (GTSs) protect hippocampal neurons after experimental traumatic brain injury (TBI) in rats. A moderate-grade TBI was made with the aid...
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The Effect of D,L-6,8-Thioctic Acid on the Volume of Cerebral Infarction in Ischemic Rat Model

Yi HJ, Lee SG, Rhee WT, Kim KM, Kim YS, Ko Y

  • KMID: 1904629
  • J Korean Neurosurg Soc.
  • 2002 Oct;32(4):363-370.
OBJECTIVE: The authors demonstrate neuroprotective effects of antioxidant in reperfusion injury using ischemic rat model and evaluate the clinical eligibility of this agent to ischemic cerebrovascular diseases. METHODS: Rat model was...
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Anti-oxidative neuroprotection by estrogens in mouse cortical cultures

Bae YH, Hwang JY, Kim YH, Koh JY

Estrogen replacement therapy in postmenopausal women may reduce the risk of Alzheimer's disease, possibly by ameliorating neuronal degeneration. In the present study, we examined the neuroprotective spectrum of estrogen against...
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