- Sensory involvement in the SOD1-G93A mouse model of amyotrophic lateral sclerosis
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Guo YS, Wu DX, Wu HR, Wu SY, Yang C, Li B, Bu H, Zhang YS, Li CY
- KMID: 1123461
- Exp Mol Med.
- 2009 Mar;41(3):140-150.
- doi: 10.3858/emm.2009.41.3.017
A subset of patients of amyotrophic lateral sclerosis (ALS) present with mutation of Cu/Zn superoxide dismutase 1 (SOD1), and such mutants caused an ALS-like disorder when expressed in rodents. These... -
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- Pitt-Hopkins Syndrome: intellectual disability due to loss of TCF4-regulated gene transcription
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Sweatt JD
- KMID: 2154240
- Exp Mol Med.
- 2013 May;45(5):e21.
TCF4 (transcription factor 4; E2-2, ITF2) is a transcription factor that when haplo-insufficient causes Pitt-Hopkins Syndrome (PTHS), an autism-spectrum disorder that is associated with pervasive developmental delay and severe intellectual... -
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- Effect of Ketamine on Apoptosis by Energy Deprivation in Astroglioma Cells using Flow Cytometry System
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Choi SJ, Kim MH, Lim SW, Gwak MS
- KMID: 1781737
- J Korean Med Sci.
- 2005 Feb;20(1):113-120.
- doi: 10.3346/jkms.2005.20.1.113
Apoptosis is a programmed, physiologic mode of cell death that plays an important role in tissue homeostasis. As for the central nervous system, ischemic insults can induce pathophysiologic cascade of... -
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