- Application of Iron Related Magnetic Resonance Imaging in the Neurological Disorders
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Kim TH, Lee JH
- KMID: 1708884
- Korean J Clin Neurophysiol.
- 2014 Jun;16(1):1-7.
- doi: 10.14253/kjcn.2014.16.1.1
Iron is an important element for brain oxygen transport, myelination, DNA synthesis and neurotransmission. However, excessive iron can generate reactive oxygen species and contribute neurotoxicity. Although brain iron deposition is... -
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- Amyloidogenic Protein of alpha-Synuclein
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Yang JE, Paik SR
- KMID: 2168245
- Hanyang Med Rev.
- 2013 May;33(2):123-129.
- doi: 10.7599/hmr.2013.33.2.123
Amyloidogenesis is the key pathological phenomenon commonly observed in various neurodegenerative disorders. alpha-Synuclein is the major constituent of Lewy bodies as a common pathological signature of Lewy body diseases (LBDs)... -
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- Misfolded Proteins in Neurodegenerative Dementias: Molecular Mechanisms
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Yang HD, Ho DH, Yi MJ, Seol W, Kim SY
- KMID: 2172233
- Dement Neurocogn Disord.
- 2012 Jun;11(2):38-52.
- doi: 10.12779/dnd.2012.11.2.38
During recent years, there has been remarkable progress with respect to the identification of molecular mechanisms and underlying pathology of neurodegenerative dementias. The latest evidence indicates that a common cause... -
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- Occupational Neurological Disorders in Korea
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Kim EA, Kang SK
- KMID: 1714064
- J Korean Med Sci.
- 2010 Dec;25(Suppl):S26-S35.
- doi: 10.3346/jkms.2010.25.S.S26
The purpose of this article was to provide a literature review of occupational neurological disorders and related research in Korea, focusing on chemical hazards. We reviewed occupational neurological disorders investigated... -
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- Autophagy and Neurodegenerative Diseases
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Paek J, Kim B
- KMID: 1813203
- J Korean Neurol Assoc.
- 2009 Aug;27(3):206-214.
Autophagy is a highly regulated cellular mechanism that results in the bulk degradation of long-lived proteins and organelles and which seems to be implicated in a variety of physiological and... -
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- Efficient Induction of Dopaminergic Neurons from Embryonic Stem Cells for Application to Parkinson's Disease
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Kim DW
- KMID: 1726141
- Yonsei Med J.
- 2004 Jun;45(Suppl):S23-S27.
- doi: 10.3349/ymj.2004.45.Suppl.23
For cell replacement therapy of neurodegenerative diseases such as Parkinson's disease (PD), methods for efficiently generating midbrain dopaminergic (DA) neurons from embryonic stem (ES) cells have been investigated. Two aspects... -
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- Application of Proteomics and Protein Chip Analysis in the Diagnosis of Neurodegenerative Disorders
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Ryu W, Choi C
- KMID: 2185762
- J Korean Neurol Assoc.
- 2003 Dec;21(6):584-599.
As we face an increase of the adult population suffering from dementia, a typical senile disorder, it is imperative to develop appropriate tools for early detection and differential diagnosis of... -
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- The Role of the Ubiquitin-Proteasome Pathway in Neurodegenerative Disorders
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Choi K, Choi C
- KMID: 2185761
- J Korean Neurol Assoc.
- 2003 Dec;21(6):573-583.
Impaired function of the Ubiquitin (Ub)/proteasome pathway is one of the molecular mechanisms underlying aging process and neurodegenerative disorders such as Parkinson's Disease and Alzheimer's Disease (AD). Among many vital... -
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