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Gamma Knife Radiosurgery on the Trigeminal Root Entry Zone for Idiopathic Trigeminal Neuralgia: Results and a Review of the Literature

Park SH, Chang JW

Trigeminal neuralgia (TN) is a chronic disorder of the trigeminal nerve characterized by repeated electrical shock-like sensations on one side of the face. It can cause severe pain in the...
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Comparison of Neuropathic Pain in Neuromyelitis Optica Spectrum Disorder and Multiple Sclerosis

Hyun JW, Jang H, Yu J, Park NY, Kim SH, Huh SY, Kim W, Park MS, Oh J, Park KD, Kim HJ

BACKGROUND AND PURPOSE: To compare the characteristics of neuropathic pain in neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS). METHODS: From 2016 to 2018, 500 patients with NMOSD and MS...
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Neuropathic Pain in Guillain-Barre Syndrome Associated with Scrub Typhus

Kang S, Lee SJ, Choi E

Guillain-Barre syndrome (GBS) is usually characterized by acute areflexic ascending paralysis with minimal sensory involvement. Only a few cases of GBS associated with scrub typhus have been reported. Previous case...
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Isolated Trigeminal Neuralgia Presented Due to Cerebellopontine Angle Epidermoid Cyst

Yim SH, Yoon B, Lee JG, Kim YD, Na SJ

Trigeminal neuralgia (TN) is a paroxysmal shock like pain restricted to the innervations of the areas of one or more trigeminal branches. The pathogenesis of TN is uncertain and typically...
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Spinal Nitric Oxide Synthase Type II Increases Neurosteroid-metabolizing Cytochrome P450c17 Expression in a Rodent Model of Neuropathic Pain

Choi SR, Beitz AJ, Lee JH

We have previously demonstrated that the neurosteroid dehydroepiandrosterone sulfate (DHEAS) induces functional potentiation of N-methyl-D-aspartate (NMDA) receptors via increases in phosphorylation of NMDA receptor GluN1 subunit (pGluN1). However, the modulatory...
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Investigation of the Neuropathic Pain Caused by Syringomyelia Associated with Chiari I Malformation

Seki T, Hamauchi S, Yamazaki M, Hida K, Yano S, Houkin K

STUDY DESIGN: Retrospective cohort study. PURPOSE: To investigate the correlation between the syrinx morphology and neuropathic pain caused by syringomyelia associated with Chiari I malformation. OVERVIEW OF LITERATURE: Neuropathic pain caused by...
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Neurovascular Compression Confirmed by 3D T2-Weighted Volume Isotropic Turbo Spin-Echo Acquisition Sequence in Trigeminal Neuralgia

Jeon SH, Kim HJ, Kang MK, Hwang SB, Kang HG, Shin BS

No abstract available.
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Inhibition of MicroRNA-15a/16 Expression Alleviates Neuropathic Pain Development through Upregulation of G Protein-Coupled Receptor Kinase 2

Li T, Wan Y, Sun L, Tao S, Chen P, Liu C, Wang K, Zhou C, Zhao G

There is accumulating evidence that microRNAs are emerging as pivotal regulators in the development and progression of neuropathic pain. MicroRNA-15a/16 (miR-15a/16) have been reported to play an important role in...
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Effects of Repetitive High Frequency Motor Cortex Transcranial Magnetic Stimulation and Cortical Disinhibition in Diabetic Patients with Neuropathic Pain: A Case Control Study

Han Y, Lee CH, Min KW, Han KA, Choi HS, Kang YJ

OBJECTIVE: To investigate the cortical disinhibition in diabetic patients with neuropathic pain and without pain. In addition, we assessed the cortical disinhibition and pain relief after repetitive transcranial magnetic stimulation...
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Gamma Knife Radiosurgery in Recurrent Trigeminal Neuralgia after Other Procedures

Lee JM, Hur BI, Choi CH

OBJECTIVES: Trigeminal neuralgia (TN) is undurable paroxysmal pain in the distribution of the fifth cranial nerve. Invasive treatment modalities for TN include microvascular decompression (MVD) and percutaneous procedures, such as,...
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Analysis of Neuropathic Pain Using Magnetic Resonance Imaging T2 Mapping of Intervertebral Disc in Chronic Low Back Pain

Ogon I, Takebayashi T, Takashima , Morita T, Iesato N, Tanimoto K, Terashima , Yoshimoto , Yamashita

STUDY DESIGN: Cross sectional study. PURPOSE: The study aimed to analyze mechanisms underlying chronic low back pain (CLBP) using magnetic resonance imaging (MRI) T2 mapping of the intervertebral disc (IVD). OVERVIEW OF...
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Treatment of Facial Neuralgia Developed after Inferior Meatal Antrostomy by Narrowing of the Inlet with Endoscopic Cartilage Graft

Yi JS, Jin HR

Inferior meatal antrostomy (IMA) is a widely performed surgical technique to treat postoperative maxillary mucocele. The method is safe and easy to perform, without major complications compared with other approaches....
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Refractory intercostal neuralgia due to intercostal schwannoma: A case report

Heo HJ, Kim YY, Lee JH, Im SM, Kim OH, Lee HG

Intercostal neuralgia is neuropathic pain that develops in the thorax and abdomen. It usually occurs as a result of injury or inflammation associated with the intercostal nerve triggered by trauma,...
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Trigeminal Neuralgia Resulting from Delayed Cervical Cord Compression after Acute Traumatic Fracture of Odontoid Process

Shim YW, Paeng SH, Lee KS, Kim ST, Lee WH

Trigeminal neuralgia is caused by compression of trigeminal nerve root and it leads to demyelination gradually. It was almost idiopathic and occurred unexpected. The upper cervical spinal cord contains the...
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Amitriptyline inhibits the MAPK/ERK and CREB pathways and proinflammatory cytokines through A3AR activation in rat neuropathic pain models

Kim Y, Kwon SY, Jung HS, Park YJ, Kim YS, In JH, Choi JW, Kim JA, Joo JD

BACKGROUND: The pain-relief properties of tricyclic antidepressants can be attributed to several actions. Recent observations suggest that adenosine is involved in the antinociceptive effect of amitriptyline. The A3 adenosine receptor...
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An integrated review on new targets in the treatment of neuropathic pain

Khangura R, Sharma J, Bali A, Singh N, Jaggi AS

Neuropathic pain is a complex chronic pain state caused by the dysfunction of somatosensory nervous system, and it affects the millions of people worldwide. At present, there are very few...
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“Post-Decompressive Neuropathy”: New-Onset Post-Laminectomy Lower Extremity Neuropathic Pain Different from the Preoperative Complaint

Boakye LA, Fourman MS, Spina NT, Laudermilch D, Lee JY

STUDY DESIGN: Level III retrospective cross-sectional study. PURPOSE: To define and characterize the presentation, symptom duration, and patient/surgical risk factors associated with ‘postdecompressive neuropathy (PDN).' OVERVIEW OF LITERATURE: PDN is characterized by...
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Risk Factors of Neuropathic Pain after Total Hip Arthroplasty

Maeda K, Sonohata M, Kitajima M, Kawano S, Mawatari M

PURPOSE: Pain caused by osteoarthritis is primarily nociceptive pain; however, it is considered that a component of this pain is due to neuropathic pain (NP). We investigated the effects of...
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A Case of Secondary Trigeminal Neuralgia Caused by Infected Postoperative Maxillary Cyst

Lee SM, Sung HK, Kang JC, Kim HJ

Postoperative maxillary cyst (POMC) is relatively common complication among patients who underwent Caldwell-Luc surgery. Patients with POMC usually have no symptoms, although cyst extension can result in bone destruction or...
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Prospective Comparison of Redo Microvascular Decompression and Percutaneous Balloon Compression as Primary Surgery for Recurrent Trigeminal Neuralgia

Chen JN, Yu WH, Du HG, Jiang L, Dong XQ, Cao J

OBJECTIVE: To prospectively compare facial pain outcomes for patients having either a repeat microvascular decompression (MVD) or percutaneous balloon compression (PBC) as their surgery for trigeminal neuralgia (TN) recurrence. METHODS: Prospective...
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