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Antiangiogenesis therapy: an update after the first decade

De Falco S

Angiogenesis is a complex biological phenomenon that forms new blood vessels from the pre-existing vasculature. Aberrant angiogenesis has been implicated in a variety of diseases such as cancer, atherosclerosis, arthritis,...
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Inhibition of trichostatin A-induced antiangiogenesis by small-interfering RNA for thrombospondin-1

Kang JH, Kim SA, Chang SY, Hong S, Hong KJ

  • KMID: 1047092
  • Exp Mol Med.
  • 2007 Jun;39(3):402-411.
Expression of thrombospondin-1 (TSP-1), which is a known inhibitor of tumor growth and angiogenesis, is reciprocally regulated by positive regulators, such as VEGF. Additionally, trichostatin A (TSA) suppresses tumor progression...
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The Role of Angiostatin, Vascular Endothelial Growth Factor, Matrix Metalloproteinase 9 and 12 in the Angiogenesis of Hepatocellular Carcinoma

Kim S, Park HS, Son HJ, Moon WS

  • KMID: 760532
  • Korean J Hepatol.
  • 2004 Mar;10(1):62-72.
BACKGROUND/AIMS: Tumor angiogenesis, a major requirement for tumor growth and metastasis, is regulated by pro- and anti-angiogenic factors. Hepatocellular carcinoma (HCC) has become a common malignant tumor worldwide. It...
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