- Clinicopathological Features of Rare BRAF Mutations in Korean Thyroid Cancer Patients
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Cho U, Oh WJ, Bae JS, Lee S, Lee YS, Park GS, Lee YS, Jung CK
- KMID: 2129598
- J Korean Med Sci.
- 2014 Aug;29(8):1054-1060.
- doi: 10.3346/jkms.2014.29.8.1054
The most common BRAF mutation in thyroid cancer is c.1799T>A (p.Val600Glu), and other BRAF mutations are rarely reported. We investigated the clinicopathological features of thyroid cancer with rare BRAF mutations.... -
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- TERT Polymorphism rs2853669 Influences on Lung Cancer Risk in the Korean Population
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Yoo SS, Do SK, Choi JE, Lee SY, Lee J, Cha SI, Kim CH, Park JY
- KMID: 2344174
- J Korean Med Sci.
- 2015 Oct;30(10):1423-1428.
- doi: 10.3346/jkms.2015.30.10.1423
Short telomeres are known as one of the risk factors for human cancers. The present study was conducted to evaluate the association between 6 polymorphisms, which were related with short... -
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- RET Fusion Genes in Korean Non-Small Cell Lung Cancer
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Yoo SS, Jin G, Jung HJ, Hong MJ, Choi JE, Jeon HS, Lee SY, Lim JO, Park JY
- KMID: 1777699
- J Korean Med Sci.
- 2013 Oct;28(10):1555-1558.
- doi: 10.3346/jkms.2013.28.10.1555
Recently, rearranged during transfection (RET) fusions have been identified in approximately 1% of non-small cell lung cancer (NSCLC). To know the prevalence of RET fusion genes in Korean NSCLCs, we... -
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- CpG Island Methylator Phenotype-High Colorectal Cancers and Their Prognostic Implications and Relationships with the Serrated Neoplasia Pathway
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Rhee YY, Kim KJ, Kang GH
- KMID: 2412153
- Gut Liver.
- 2017 Jan;11(1):38-46.
- doi: 10.5009/gnl15535
The concept of a CpG island methylator phenotype (CIMP) was first introduced by Toyota and Issa to describe a subset of colorectal cancers (CRCs) with concurrent hypermethylation of multiple CpG... -
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- Interactive Effect of Smoking and NQO1 Haplotypes on Lung Cancer Risk
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Kim JH, Hong YC
- KMID: 2133296
- J Korean Med Sci.
- 2015 Mar;30(3):221-226.
- doi: 10.3346/jkms.2015.30.3.221
The role of genetic polymorphisms of NAD(P)H:quinone oxidoreductase 1 (NQO1), which is known to be related to carcinogen metabolism and oxidative status, was evaluated for lung cancer development. The genotypes... -
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- The association of 5-alpha reductase type 2 (SRD5A2) gene polymorphisms with prostate cancer in a Korean population
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Choi SY, Kim HJ, Cheong HS, Myung SC
- KMID: 2070265
- Korean J Urol.
- 2015 Jan;56(1):19-30.
- doi: 10.4111/kju.2015.56.1.19
PURPOSE: Steroid 5-alpha reductase type 2 (SRD5A2) modifies testosterone to dihydrotestosterone (DHT) in the prostate. Single-nucleotide polymorphisms (SNPs) of the SRD5A2 gene might affect DHT. We sought to understand the... -
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- High Frequency of Microsatellite Instability in Intestinal-type Gastric Cancer in Korean Patients
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Choe WH, Lee SY, Lee JH, Shim SG, Kim YH, Rhee PL, Rhee JC, Ki CS, Kim JW, Song SY, Kim JJ
- KMID: 1718032
- Korean J Intern Med.
- 2005 Jun;20(2):116-122.
- doi: 10.3904/kjim.2005.20.2.116
BACKGROUND: Although there have been some reports on microsatellite alterations in gastric cancer, findings are inconsistent regarding the associations between histological classification and microsatellite instability (MSI). In the present study,... -
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- Polymorphisms of CYP1A1 and GSTM1 Genes and Susceptibility to Oral Cancer
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Cha IH, Park JY, Chung WY, Choi MA, Kim HJ, Park KK
- KMID: 1779525
- Yonsei Med J.
- 2007 Apr;48(2):233-239.
- doi: 10.3349/ymj.2007.48.2.233
PURPOSE: Oral cancer is the fifth most common form of cancer in the world and comprises 6.5% of all cancer deaths. Since one of the major risk factors for oral... -
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- Gene-Diet Interaction on Cancer Risk in Epidemiological Studies
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Lee SA
- KMID: 1105308
- J Prev Med Public Health.
- 2009 Nov;42(6):360-370.
- doi: 10.3961/jpmph.2009.42.6.360
Genetic factors clearly play a role in carcinogenesis, but migrant studies provide unequivocal evidence that environmental factors are critical in defining cancer risk. Therefore, one may expect that the lower... -
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