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Global prevalence of classic phenylketonuria based on Neonatal Screening Program Data: systematic review and meta-analysis

Shoraka HR, Haghdoost AA, Baneshi MR, Bagherinezhad Z, Zolala F

Phenylketonuria is a disease caused by congenital defects in phenylalanine metabolism that leads to irreversible nerve cell damage. However, its detection in the early days of life can reduce its...
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Prenatal diagnosis of harlequin ichthyosis: a case report

Vijayakumari M, Reddy DK, Routhu M, Vuchuru M, Reddy NS

Harlequin ichthyosis (HI) is a rare and severe form of ichthyosis and is characterized by thickened, hard, armor-like plates of skin that cover the entire body. This disease is caused...
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The relation between serum levels of epidermal growth factor and necrotizing enterocolitis in preterm neonates

Ahmed HM, Kamel NM

PURPOSE: Necrotizing enterocolitis (NEC) is one of the most serious complications of prematurity. Many risk factors can contribute to the development of NEC. The epidermal growth factor (EGF) plays a...
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Iodine Deficiency in Neonates: Where Do We Stand After a Quarter Century of Initiating Iodization Programs?

Jafri L, Majid H, Ahmed S, Siddiqui I, Ghani F, Khan AH

An observational study was conducted at the Section of Clinical Chemistry, Department of Pathology and Laboratory Medicine, to assess the iodine status using the World Health Organization (WHO), United Nations...
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Transfusion practice in neonates

Kim DH

Neonates, especially extremely low birth weight infants, are among the groups of patients undergoing transfusion frequently. Since they are exposed to higher specific transfusion risks compared to the patients of...
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Descending Aorta Blood Flow Characteristics before the Development of Necrotizing Enterocolitis in Preterm Neonates

Kim KM, Kim HS, Yoon JH, Lee EJ, Yum SK, Moon CJ, Youn YA, Kwun YJ, Lee JY, Sung IK

PURPOSE: To investigate the hemodynamic risk factors for necrotizing enterocolitis (NEC), we analyzed the characteristics of descending aorta (DA) blood flow in preterm neonates, who later developed NEC. METHODS: This was...
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The Association between Vitamin D Levels and Neonatal Early-onset Sepsis : A Systematic Review and Meta-analysis

Lee SY, Kim HE, An SH

BACKGROUND: Vitamin D has been associated with sepsis in pediatric and adult patients. The association with neonates is unclear. This systematic review and meta-analysis examined the effect of neonatal and...
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Effect of Nutritional Support on Postoperative Growth Velocity of Neonates in Neonatal Intensive Care Unit

Jo HI, Sul JY, Park JB

PURPOSE: This study aimed to evaluate the relationship between nutritional support and growth velocity after abdominal surgery in neonates. METHODS: The electronic medical records of 45 neonates who underwent abdominal surgery...
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Safety of delayed umbilical cord clamping in preterm neonates of less than 34 weeks of gestation: a randomized controlled trial

Rana A, Agarwal K, Ramji S, Gandhi G, Sahu L

OBJECTIVE: There is concern regarding the safety of delayed cord clamping (DCC) in babies born at less than 34 weeks' gestation. Therefore, the primary objective of this study was to...
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The Effect of Ethnicity on Wideband Absorbance of Neonates with Healthy Middle Ear Functions in Malaysia: A Preliminary Study

Wali HA, Mazlan R

BACKGROUND AND OBJECTIVES: Although ethnicity effect on wideband absorbance (WBA) findings was evident for adults, its effect on neonates has not been established yet. This study aimed to investigate the...
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High Prevalence of Rotavirus G4P[6] Genotypes among Neonates in Two Korean Hospitals

Kim JS, Kim SM, Kim HS

BACKGROUND: The introduction of rotavirus vaccines has decreased the prevalence of rotavirus infections and might have changed the distribution of rotavirus genotypes. However, neonates are not eligible for vaccination and,...
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Evaluation and Management of Neonates with Possible Congenital Zika Virus Infection

Yun KW

Zika virus infection is, typically, either asymptomatic or causes mild illness; however, it may present severe clinical manifestations in neonates. Zika virus can be transmitted from a pregnant woman to...
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Contributing Factors on Pharmacokinetic Variability in Critically Ill Neonates

An SH

Neonates have large inter-individual variability in pharmacokinetic parameters of many drugs due to developmental differences. The aim of this study was to investigate the factors affecting the pharmacokinetic parameters of...
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Applying the Bacterial Meningitis Score in Neonates Diagnosed Meningitis: A Single Center Experience

Park SY, Seo KH, Lee JM, Lee ES, Kim S

PURPOSE: To identify the factors associated with differential diagnosis of neonatal bacterial meningitis at the earliest opportunities possible and to evaluate the value of the bacterial meningitis score especially in...
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Does anaesthesia in mothers during delivery affect bilirubin levels in their neonates?

El-Kabbany ZA, Toaima NN, Toaima TN, EL-Din MY

PURPOSE: This study aimed to assess whether different anesthetic techniques and oxytocin use applied during delivery affect transcutaneous bilirubin levels during the first 24 hours in neonates. METHODS: A total of...
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Clinical Characteristics and Outcomes of the First Episode of Urinary Tract Infection in Neonates and Infants Younger than 2 Months of Age

Cheng JY

PURPOSE: The American Academy of Pediatrics provides guidelines for managing febrile urinary tract infection (UTI) in infants and children 2-24 months old, but little guidance is offered regarding UTIs in...
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Human Umbilical Cord Blood CD34-Positive Cells as Predictors of the Incidence and Short-Term Outcome of Neonatal Hypoxic-Ischemic Encephalopathy: A Pilot Study

Hassanein , Nasr Eldin MH, Amer HA, Abdelhamid AE, El Houssinie M, Ibrahim A

BACKGROUND AND PURPOSE: Neonatal hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of neurological handicap in developing countries. Human umbilical cord blood (hUCB) CD34-positive (CD34⁺) stem cells exhibit the...
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RSV Outbreak at a Single Postpartum Care Center in Gyeongsangbukdo

Hong SJ, Kim DK, Lee DS, Cho SM, Choi SM

PURPOSE: We performed an analysis of the RSV outbreak in a postpartum center in Gyeongsangbukdo to provide preliminary data for health and hygiene management of postpartum care centers. METHODS: All of...
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Clinical Characteristics Associated with Blood Culture Contamination in Neonates

Jung MY, Son OS, Hong YR, Oh CE

PURPOSE: This study was aimed to investigate the contamination rates of blood culture in a neonatal intensive care unit (NICU) and to examine the clinical characteristics related to the contamination. METHODS:...
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Neonatal Bacterial Conjunctivitis: Pathogenic Distribution

Ahn SH, Lee YK, Ko SY, Shin SM

PURPOSE: To study the causative microorganism of neonatal bacterial conjunctivitis and its correlation with maternal factors. METHODS: We retrospectively reviewed the medical records of 55 neonates diagnosed with bacterial conjunctivitis and...
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