- Comparison between weekly versus 3-weekly paclitaxel in combination with carboplatin as neoadjuvant chemotherapy in advanced ovarian cancer
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Kim YN, Lee YJ, Lee JY, Nam EJ, Kim SW, Kim S, Kim YT
- KMID: 2470873
- J Gynecol Oncol.
- 2020 Mar;31(2):e23.
- doi: 10.3802/jgo.2020.31.e23
OBJECTIVE: To compare the efficacy and toxicity of dose-dense weekly paclitaxel and 3-weekly carboplatin (ddPC) as neoadjuvant chemotherapy (NAC) with the standard 3-weekly regimen. METHODS: A retrospective study of patients diagnosed... -
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- Efficacy and safety of neoadjuvant chemotherapy versus primary debulking surgery in patients with ovarian cancer: a meta-analysis
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Lv X, Cui S, Zhang X, Ren C
- KMID: 2470865
- J Gynecol Oncol.
- 2020 Mar;31(2):e12.
- doi: 10.3802/jgo.2020.31.e12
OBJECTIVE: Neoadjuvant chemotherapy (NACT) for the treatment of epithelial ovarian cancer (EOC) has remained controversial. This meta-analysis was performed to systematically assess the efficacy and safety of NACT versus primary... -
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- Extended distal pancreatectomy with thoracic wall resection after neoadjuvant FOLFIRINOX: Is there a limit of resection for pancreatic cancer after downstaging?
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Giuliani T, López Rubio M, Montalvá Oron E, Maupoey Ibañez J, Boscá Robledo A, López Valdivia C, Pérez Rojas J, Lopez Andujar R
- KMID: 2471196
- Ann Hepatobiliary Pancreat Surg.
- 2020 Feb;24(1):90-96.
- doi: 10.14701/ahbps.2020.24.1.90
Indications and outcomes of extended pancreatectomies have been recently appraised by the International Study Group for Pancreatic Surgery. However, no definitive conclusions have been drawn, particularly in the setting of... -
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- Assessment of the Prognostic Staging System of American Joint Committee on Cancer 8th Edition for Breast Cancer: Comparisons with the Conventional Anatomic Staging System
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Kim EJ, Park HS, Kim JY, Kim SI, Cho YU, Park BW
- KMID: 2470882
- J Breast Cancer.
- 2020 Feb;23(1):59-68.
- doi: 10.4048/jbc.2020.23.e9
PURPOSE: The 8th edition of the American Joint Committee on Cancer (AJCC) staging manual introduced a new prognostic staging system for breast cancer. This study aimed to evaluate the changes... -
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- Analysis of Tau Protein Expression in Predicting Pathological Complete Response to Neoadjuvant Chemotherapy in Different Molecular Subtypes of Breast Cancer
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Lei C, Yang C, Xia B, Ji F, Zhang Y, Gao H, Xiong Q, Lin Y, Zhuang X, Zhang L, Zhu T, Cheng M, Yang M, Wang K
- KMID: 2470881
- J Breast Cancer.
- 2020 Feb;23(1):47-58.
- doi: 10.4048/jbc.2020.23.e11
PURPOSE: Tau is a microtubule-associated protein that can be found in both normal and abnormal breast cells. Whether the expression of Tau protein can predict the response to neoadjuvant chemotherapy... -
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- Characteristics and survival of ovarian cancer patients treated with neoadjuvant chemotherapy but not undergoing interval debulking surgery
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Liu YL, Filippova OT, Zhou Q, Iasonos A, Chi DS, Zivanovic O, Sonoda Y, Gardner GJ, Broach VA, O'Cearbhaill RE, Konner JA, Aghajanian C, Long Roche K, Tew WP
- KMID: 2465191
- J Gynecol Oncol.
- 2020 Jan;31(1):e17.
- doi: 10.3802/jgo.2020.31.e17
OBJECTIVE: Neoadjuvant chemotherapy (NACT) followed by interval debulking surgery (IDS) confers similar outcomes as primary debulking surgery and chemotherapy. Little is known about patients who receive NACT but do not... -
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- Predictive and Prognostic Roles of Pathological Indicators for Patients with Breast Cancer on Neoadjuvant Chemotherapy
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Li X, Wang M, Wang M, Yu X, Guo J, Sun T, Yao L, Zhang Q, Xu Y
- KMID: 2470889
- J Breast Cancer.
- 2019 Dec;22(4):497-521.
- doi: 10.4048/jbc.2019.22.e49
Currently, neoadjuvant chemotherapy is a standard therapeutic strategy for breast cancer, as it can provide timely and individualized chemo-sensitivity information and is beneficial for custom-designing subsequent treatment strategies. To accurately... -
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- Impact of Adjuvant Chemotherapy Completion on Oncologic Outcomes in ypTNMstage 2 Rectal Cancer Patients
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Park YY, Lee KY, Kim NK, Lee SB, Kim GR, Min BS, Oh ST
- KMID: 2468856
- Ann Coloproctol.
- 2019 Dec;35(6):335-341.
- doi: 10.3393/ac.2019.03.10
PURPOSE: Adjuvant chemotherapy (aCT) in rectal cancer patients who have undergone curative resection after neoadjuvant chemoradiation (nCRT) is controversial. We aimed to investigate the benefits of using aCT and the... -
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- Analysis of Intestinal Mucosal Microbiome Changes before and after Chemoradiation in Locally Advanced Rectal Cancer Patients
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Seo I, Bae SU, Kim S, Jeong WK, Baek SK
- KMID: 2468023
- J Bacteriol Virol.
- 2019 Dec;49(4):162-175.
- doi: 10.4167/jbv.2019.49.4.162
PURPOSE: Dysbiosis of gut microbiota has been reported to participate in the pathogenesis of colorectal cancer, but changes in microbiota due to radiotherapy have not been studied. In this study,... -
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- Comprehensive Cancer Panel Sequencing Defines Genetic Diversity and Changes in the Mutational Characteristics of Pancreatic Cancer Patients Receiving Neoadjuvant Treatment
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Yoon KA, Woo SM, Kim YH, Kong SY, Lee MK, Han SS, Kim TH, Lee WJ, Park SJ
- KMID: 2464315
- Gut Liver.
- 2019 Nov;13(6):683-689.
- doi: 10.5009/gnl18355
BACKGROUND/AIMS: Pancreatic ductal adenocarcinoma (PDA) is associated with an extremely poor prognosis. This study assessed the genetic diversity among patients with PDA and compared their mutational profiles before and after... -
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- Efficacy and Feasibility of Adding Induction Chemotherapy to Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer: A Phase II Clinical Trial
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Nasrolahi , Mirzaei S, Mohammadianpanah M, Bananzadeh AM, Mokhtari M, Sasani MR, Mosalaei A, Omidvari S, Ansari M, Ahmadloo N, Hamedi SH, Khanjani N
- KMID: 2464338
- Ann Coloproctol.
- 2019 Oct;35(5):242-248.
- doi: 10.3393/ac.2018.09.06
PURPOSE: Currently, neoadjuvant chemoradiation (CRT) followed by total mesorectal resection is considered the standard of care for treating locally advanced rectal cancer. This study aimed to investigate the efficacy and... -
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- Lymph Node Status after Neoadjuvant Chemoradiation Therapy for Esophageal Cancer according to Radiation Field Coverage
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Kim SY, Park S, Park IK, Kim YT, Kang CH
- KMID: 2460469
- Korean J Thorac Cardiovasc Surg.
- 2019 Oct;52(5):353-359.
- doi: 10.5090/kjtcs.2019.52.5.353
BACKGROUND: To explore the effect of radiation on metastatic lymph nodes (LNs) after neoadjuvant chemoradiation therapy (nCRT), we examined the metastatic features of LNs according to their inclusion in the... -
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- Potential Benefits of Neoadjuvant Chemotherapy in Clinically Node-Positive Luminal Subtypeâ» Breast Cancer
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Kim HS, Yoo TK, Park WC, Chae BJ
- KMID: 2458862
- J Breast Cancer.
- 2019 Sep;22(3):412-424.
- doi: 10.4048/jbc.2019.22.e35
PURPOSE: Neoadjuvant chemotherapy (NAC) is less effective for luminal breast cancer because luminal breast cancer has a lower rate of pathological complete response (pCR) after NAC than human epidermal growth... -
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- Weight Gain during Neoadjuvant Chemotherapy is Associated with Worse Outcome among the Patients with Operable Breast Cancer
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Fang Q, Huang J, Gan L, Shen K, Chen X, Wu B
- KMID: 2458861
- J Breast Cancer.
- 2019 Sep;22(3):399-411.
- doi: 10.4048/jbc.2019.22.e37
PURPOSE: This study was aimed at identifying the influence of initial weight and weight change during neoadjuvant chemotherapy (NAC) on pathologic complete response (pCR) and long-term survival in Chinese patients... -
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- Treatment strategies for patients with advanced ovarian cancer undergoing neoadjuvant chemotherapy: interval debulking surgery or additional chemotherapy?
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Yoneoka Y, Ishikawa M, Uehara T, Shimizu H, Uno M, Murakami T, Kato T
- KMID: 2457157
- J Gynecol Oncol.
- 2019 Sep;30(5):e81.
- doi: 10.3802/jgo.2019.30.e81
OBJECTIVE: To treat advanced ovarian cancer, interval debulking surgery (IDS) is performed after 3 cycles each of neoadjuvant chemotherapy (NAC) and postoperative chemotherapy (IDS group). If we expect that complete... -
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- Response Assessment with MRI after Chemoradiotherapy in Rectal Cancer: Current Evidences
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Seo N, Kim H, Cho MS, Lim JS
- KMID: 2467019
- Korean J Radiol.
- 2019 Jul;20(7):1003-1018.
- doi: 10.3348/kjr.2018.0611
Baseline magnetic resonance imaging (MRI) has become the primary staging modality for surgical plans and stratification of patient populations for more efficient neoadjuvant treatment. Patients who exhibit a complete response... -
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- Effect of Platinum-Based Chemotherapy on PD-L1 Expression on Tumor Cells in Non-small Cell Lung Cancer
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Shin J, Chung JH, Kim SH, Lee KS, Suh KJ, Lee JY, Kim JW, Lee JO, Kim JW, Kim YJ, Lee KW, Kim JH, Bang SM, Lee JS
- KMID: 2454300
- Cancer Res Treat.
- 2019 Jul;51(3):1086-1097.
- doi: 10.4143/crt.2018.537
PURPOSE: Programmed death-1 (PD-1)/PD-1 ligand (PD-L1) axis blockades have revolutionized the treatment of advanced non-small cell lung cancer (NSCLC). We assessed the effect of platinum-based chemotherapy on tumor PD-L1 expression... -
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- Preliminary results of entire pleural intensity-modulated radiotherapy in a neoadjuvant setting for resectable malignant mesothelioma
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Hong JH, Lee HC, Choi KH, Moon SW, Kim KS, Hong SH, Hong JY, Kim YS, Multidisciplinary Team of Lung Cancer in Seoul St. Mary's Hospital
- KMID: 2452570
- Radiat Oncol J.
- 2019 Jun;37(2):101-109.
- doi: 10.3857/roj.2019.00150
PURPOSE: The purpose of this study is to evaluate the safety and efficacy of the multimodality treatment with neoadjuvant intensity-modulated radiotherapy (IMRT) for resectable clinical T1-3N0-1M0 malignant pleural mesothelioma (MPM). MATERIALS... -
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- Prognostic Factors in Patients with Locally Advanced Breast Cancer Treated by Neoadjuvant Chemotherapy
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Jaegal M, Kang SJ, Ryu YJ, Cho JS, Park MH, Yoon JH
- KMID: 2451796
- J Breast Dis.
- 2019 Jun;7(1):23-29.
- doi: 10.14449/jbd.2019.7.1.23
PURPOSE: Neoadjuvant chemotherapy (NAC) has become the standard treatment for patients with locally advanced breast cancer. The purpose of this study was to evaluate prognosis according to molecular subtype and... -
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- Human Epidermal Growth Factor Receptor 2-positive Mucinous Carcinoma with Signet Ring Cell Differentiation, Which Showed Complete Response after Neoadjuvant Chemotherapy
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Jang Y, Cho EY, Cho SY
- KMID: 2450126
- J Breast Cancer.
- 2019 Jun;22(2):336-340.
- doi: 10.4048/jbc.2019.22.e17
Mucinous carcinoma (MC) is a rare subtype of breast cancer, which is composed of tumor cells floating in the abundant extracellular mucin. This form of cancer is usually estrogen receptor/progesterone... -
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