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Inhibition of melanogenesis by sodium 2-mercaptoethanesulfonate

Kim JH, Oh CT, Kwon TR, Kim JH, Bak DH, Kim H, Park WS, Kim BJ

Sodium 2-mercaptoethanesulfonate (mesna) is a protective agent that is widely used in medicine because of its antioxidant effects. Recently, reactive oxygen species (ROS) were shown to increase pigmentation. Thus, ROS...
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Thyroid-Associated Orbitopathy: Evaluating Microstructural Changes of Extraocular Muscles and Optic Nerves Using Readout-Segmented Echo-Planar Imaging-Based Diffusion Tensor Imaging

Chen HH, Hu H, Chen W, Cui D, Xu XQ, Wu FY, Yang T

OBJECTIVE: We aimed to investigate the ability of readout-segmented echo-planar imaging (rs-EPI)-based diffusion tensor imaging (DTI) in assessing the microstructural change of extraocular muscles (EOMs) and optic nerves in patients...
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Prediction Model for Nursing Work Outcome of Nurses: Focused on Positive Psychological Capital

Lee SN, Kim JA

PURPOSE: The purpose of this study was to construct and test a structural equation model on nursing work outcomes based on Youssef and Luthans' positive psychological capital and integrated conceptual...
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Relationship between job stress, health functional food selection attributes, and consumption values among workers for information technology in Gyeonggi area

Jung JE, Kim SE

PURPOSE: This study examined the relationship between job stress, attributes of health functional food (HFF) selection, and consumption values for information technology (IT) workers, and analyzed the factors influencing the...
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A Structural Model Explaining the Health Behaviors among Adults with Metabolic Syndrome: Theory of Planned Behavior Approach

Jang T, Song R

PURPOSE: This study aimed to identify the factors explaining the performance of health behaviors among adults with metabolic syndrome based on the theory of planned behavior. METHODS: A total of 218...
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Mediating Effects of Self-Care Competence on the Relationship between Uncertainty and Quality of Life in Hemodialysis Patients

Chae YJ, Ahn JH, Kang KP, Jo E

PURPOSE: This study aimed to explore the mediating effect of self-care competence on the relationships between uncertainty, self-care competence, and quality of life in patients undergoing hemodialysis. METHODS: This study used...
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Mediating Effects of Resilience between Nurse's Character and Happiness for Nurses in General Hospitals

Han S, Oh J, Huh B, Kim H

PURPOSE: This study was done to identify the mediating effect of resilience on the relationship between nurse's character and happiness for nurses in general hospitals. METHODS: Participants were 139 nurses working...
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Effects of Gamma-Glutamyl Transferase on Stroke Occurrence Mediated by Atrial Fibrillation

Yang W, Kang DW, Lee SH

BACKGROUND AND PURPOSE: Gamma-glutamyl transferase (GGT) is reported to be associated with stroke independently of the conventional risk factors. However, the underlying mechanism remains to be identified. This study focused...
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Ezrin-radixin-moesin proteins are regulated by Akt-GSK3β signaling in the rat nucleus accumbens core

Kim WY, Cai WT, Jang JK, Kim JH

The ezrin-radixin-moesin (ERM) proteins are a family of membrane-associated proteins known to play roles in cell-shape determination as well as in signaling pathways. We have previously shown that amphetamine decreases...
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¹H-NMR Analysis of Metabolic Changes Induced by Snf1/AMP-Activated Protein Kinase During Environmental Stress Responses

Kim J, Oh J, Yoon DH, Sung GH

AMP-activated protein kinase sucrose non-fermenting 1 (Snf1) is a representative regulator of energy status that maintains cellular energy homeostasis. In addition, Snf1 is involved in the mediation of environmental stress...
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Effects of Public Health Service Impartiality on Subjective Health Happiness: Mediated Effect of Public Health Service Quality

Moon SM

BACKGROUND: The purpose of this study is to analyze the effect of impartiality in providing public health services on subjective health happiness and the mediated effects of public health service...
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Pharmacogenetics and Depression: A Critical Perspective

Corponi F, Fabbri C, Serretti A

Depression leads the higher personal and socio-economical burden within psychiatric disorders. Despite the fact that over 40 antidepressants (ADs) are available, suboptimal response still poses a major challenge and is...
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The Causal Relationships among Staff Nurses' Job Stress Factors, Patient Safety Culture Perception and Patient Safety Nursing Activities in a University Hospital

Kim MK, Lee SM

PURPOSE: The objective of this study was to explore the causal relationships among staff nurses' job stress factors, patient safety culture perception, and patient safety nursing activities through path analysis. METHODS:...
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Impact of incivility experienced by dental hygienists on organizational achievement-as a mediating effect of emotional exhaustion

Cho MM, Kim JB, Kwun HS, Kang CW, Lee MK, Yun JW, Jeong HJ, Lee JH

OBJECTIVES: Workplace incivility is experienced by dental hygienists, who perform a variety of tasks and roles in dentistry. Therefore, to enhance the performance of dental and medical institutions, it is...
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Factors associated with Interpersonal Relationship Ability of Undergraduates: A Mediation Analysis of Smartphone Addiction Tendency

Kwon EJ, Han KS

PURPOSE: The aims of this study were to evaluate a hypothetical model explaining undergraduates' interpersonal relationship ability associated with the stress of life, self-esteem, and their communication ability and to...
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Suicidal Ideation among Older People by Different Living Arrangement: The Mediating Effect of Pleasurable Activities

Kim B, Lim S, Hong W, Kim H

PURPOSE: The purpose of this study was to examine mediating effects of pleasurable activities on the relationship between depression and suicidal ideation among the elderly moderated by living arrangement such...
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The Effect of an Empathy Education Program on Nursing Students' Empathy Ability, Interpersonal Ability, and Caring

Jeong JO, Kim S

PURPOSE: This study aimed to develop and evaluate the effects of an empathy education program for undergraduate nursing students. METHODS: The study employed a non-equivalent control group pretest-posttest design. A total...
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Impact of Depression on Medication Adherence of Patients with Systemic Lupus Erythematosus: Focusing on Mediating Effect of Self-Efficacy and Belief about Medication

Lee SJ, Ju HO

PURPOSE: The purpose of this study was to determine the mediating effects of self-efficacy and the belief about medication on the association between depression and medication adherence in patients with...
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The Influence of Job Stress, Self-Esteem, and Resilience on the Field Adaptation in Newly Graduated Nurses

Son JE, Kim SH

PURPOSE: This study aims to determine the relation among job stress, self-esteem, resilience, and field adaptation of the newly graduated nurses, through which an effective mediation strategy toward field adaptation...
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The Mediating Effects of Learning Motivation on the Association between Perceived Stress and Positive-Deactivating Academic Emotions in Nursing Students Undergoing Skills Training

Wang W, Xu H, Wang B, Zhu E

PURPOSE: Nursing students experience a high degree of perceived stress during skills training. The resulting academic sentiment is worthy of research. This study examined the learning motivation as a mediator...
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