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Melixyloidin, A New Acridone Alkaloid from Melicope xanthoxyloides Leaves

Saputri RD, Tanjung M, Tjahjandarie TS

A new acridone alkaloid, melixyloidin (1), and two known alkaloids (2-3) were isolated from Melicope xanthoxyloides (F. Muell) T.G. Hartley leaves. The structure of melixyloidin were elucidated using NMR...
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Sesbagrandiflorain F, a New 2-Arylbenzofuran from the Stem Bark of Sesbania grandiflora L.

Tanjung M, Aldin MF, Tjahjandarie TS, Rahayu DO, Gunawan ANI, Saputri RD

Sesbagrandiflorain F (1), a novel 2-arylbenzofuran, and two more 2-arylbenzofurans (2-3), were isolated from the stem bark of Sesbania grandiflora L. Based on information HRESIMS data, 1D, and 2D NMR...
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A Cipadesin Limonoid and a Tirucallane Triterpene from the Fruit of Sandoricum koetjape and their Inhibitory Properties against Receptor Tyrosine Kinases

Rachmadhaningtiyas DA, Heliawati L, Hermawati E, Syah YM

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A New Phenolic Compound from Lespedeza tomentosa

Jang HS, Choi SY, Yang H, Kim MJ, Chun W, Kwon Y

A new phenolic compound and three known flavonoids isolated from the MeOH extracts of Lespedeza tomentosa. Based on spectral data, the isolated compounds were identified as methyl 4,5-dihydroxy-3-methoxy-2-(3-methylbut-2-en-1-yl)benzoate (1), 1-methoxylespeflorin...
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Viscum album and its Constituents Downregulate MMP-13 Expression in Chondrocytes and Protect Cartilage Degradation

Lee JH, Kwon YS, Jung DY, Kim NY, Lim H, Kim HP

Under some pathological conditions such as osteoarthritis, matrix metalloproteinases (MMPs) including MMP-13 have an important role in degrading cartilage materials. When the regulatory effects of some herbal extracts on MMP-13 expression...
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Anti-inflammatory and Cytotoxic Activities of Phenolic Compounds from Broussonetia kazinoki

Vu NK, Le TT, Woo MH, Min BS

The phytochemical investigation of Broussonetia kazinoki roots led to the isolation of ten compounds, including six flavonoids (1–6), two lignans (7 and 8), and two coumarins (9 and 10) by...
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A Short Review on the Chemistry, Pharmacological Properties and Patents of Obovatol and Obovatal (Neolignans) from Magnolia obovata

Chan EWC, Wong SK, Chan HT

This short review on the chemistry, pharmacological properties and patents of obovatol and obovatal from Magnolia obovata is the first publication. Pharmacological properties are focused on anti-cancer, antiinflammatory, anti-platelet and...
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Sophora flavescens Extracts Have Therapeutic Effects on Overactive Bladder Syndrome by Potentiation of Large-Conductance Calcium-Activated Potassium Channel

Jo H, Lee HJ, Jang SJ, Moh SH, Cheong JH, Park CS

Sophora flavescens Ait. (Fabaceae) is a medicinal plant widely founded in Northeast Asia, and its dried root (Kushen) has been used as a traditional Chinese herbal medicine. The therapeutic effects...
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Optimization of Cultivation and Extraction Conditions of Pupae-Cordyceps for Cordycepin Production

Turk A, Kim BS, Ko SM, Yeon SW, Ryu SH, Kim YG, Hwang BY, Lee MK

Cordycepin is a characteristic bioactive compound of Cordyceps militaris with various beneficial effects. Cordyceps grows on both grains and insects, and the content of cordycepin varies depending on the cultivation...
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β-Patchoulene: Conversion from Patchouli Alcohol by Acid Catalysts and its In silico Anti-inflammatory Study

F, Soekamto NH, Firdausiah S, Rasyid H, Rifai A

β-patchoulene (β-PAE) is a tricyclic sesquiterpene which performed many potential bioactivities and can be found in patchouli oil but in very low concentration. This study aimed to obtained β-PAE in...
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Neuroprotective Effects of N-Acetyldopamine Dimers from Cicadidae Periostracum

Thapa P, Katila N, Choi H, Han AR, Cho DY, Nam JW

The chemical investigation of the 90% EtOH extract from Cicadidae Periostracum led to the isolation and identification of seven known N-acetyldopamine dimers (1-7). These compounds were identified by comparing mass...
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6-O-Galloylsalidroside, an Active Ingredient from Acer tegmentosum, Ameliorates Alcoholic Steatosis and Liver Injury in a Mouse Model of Chronic Ethanol Consumption

Kim YH, Woo DC, Ra M, Jung S, Kim KH, Lee Y

We have previously reported that Acer tegmentosum extract, which is traditionally used in Korea to reduce alcohol-related liver injury, suppresses liver inflammation caused by excessive alcohol consumption and might improve...
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