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Fermented Product Extract with Lentinus edodes Attenuate the Inflammatory Mediators Releases and Free Radical Production

Shim SY, Lee M

Lentinus edodes contains functional metabolites such as polysaccharopeptides, lectins, and secondary metabolites. Fermented soybean paste is representative fermented materials in Korea, and is gradually increasing due to various biological activities....
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The Pharmacological Properties of Silymarin and Its Constituents

Antika LD, Dewi RM

Silymarin is a standardized extract obtained from the seeds and fruits of Silybum marianum L., or commonly called milk thistle, a member of Carduus marianum family that contains mix of...
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Bio-guided Isolation of Natural Iron Chelators from Mangifera indica Leaves and their Comparative Study to Desferal®

Suliman SN, ElNaggar MH, Elsbaey M, El-Gamil MM, Badria FA

Through bio-guided isolation, two natural iron chelators were isolated from Mangifera indica L. leaves, identified as mangiferin (1) and iriflophenone-3-C-β-D-glucoside (2). Their iron-chelating activity was compared to that of Desferal®...
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Steroidal Saponins from Dracaena humilis (Dracaenaceae) and their Chemotaxonomic Significance

Mouzié CM, Ponou BK, Fouedjou RT, Teponno RB, Tapondjou LA

A new steroidal saponin, (23S,24S)-spirosta-5,25(27)-diene-1β,3β,23,24-tetrol 1-O-((2,3-diacetyl-α-Lrhamnopyranosyl)-(1→2)-[β-D-xylopyranosyl-(1→3)]-α-L-arabinopyranoside)-24-O-β-D-glucopyranoside (humilisoside) together with the known β-sitosterol 3-O-glucopyranoside, adenosine, dioscin, and methylprotodioscin were isolated from the leaves of Dracaena humilis. Their structures were elucidated by...
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The Use of qNMR for Quality Control of Coumarin-based Pharmaceuticals and Plant Medicines

Crocoli LC, Molon VB, Moura S

The Coumarin (1,2-benzopyrone) is the main secondary metabolite of Mikania laevigata Sch. Beep ex Baker and Mikania glomerata Spreng., which are popularly known as guaco. These plants have been used...
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A Cipadesin Limonoid and a Tirucallane Triterpene from the Fruit of Sandoricum koetjape and their Inhibitory Properties against Receptor Tyrosine Kinases

Rachmadhaningtiyas DA, Heliawati L, Hermawati E, Syah YM

A new cipadesin limonoid, i.e. 3-epi-cipadonoid C (1), and a new tirucallane triterpene, i.e. hispidol B 3-palmitate (3), have been isolated from the seeds and fruit peels extract of Sandoricum...
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Ethno-Pharmacological Profile of Corallium Rubrum L., an Important Marine Drug, in the Unani System of Medicine

Anas M, Zakir M, Maseehullah M, Kazmi MH

Since ancient times, various herbal medicines have been used in folk medicine to treat a variety of diseases. While the majority of drugs belong to the Kingdom of Plantae, some...
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In Silico Analysis of Potential Antidiabetic Phytochemicals from Matricaria chamomilla L. against PTP1B and Aldose Reductase for Type 2 Diabetes Mellitus and its Complications

Hariftyani AS, Kurniawati LA, Khaerunnisa S, Veterini AS, Setiawati Y, Awaluddin R

Type 2 diabetes mellitus (T2DM) and its complications are important noncommunicable diseases with high mortality rates. Protein tyrosine phosphatase 1B (PTP1B) and aldose reductase inhibitors are recently approached and advanced...
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Suppressive Impact of Ginsenoside-Rg2 on Catecholamine Secretion from the Rat Adrenal Medulla

Ha KS, Kim KH, Lim HJ, Ki YJ, Koh YY, Lim DY

This study was designed to characterize the effect of ginsenoside-Rg2 (Rg2), one of panaxatriol saponins isolated from Korean ginseng root, on the release of catecholamines (CA) in the perfused model...
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