- Global Regulators to Activate Silent Biosynthetic Gene Clusters
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Shim SH
- KMID: 2507446
- Nat Prod Sci.
- 2020 Sep;26(3):183-190.
- doi: 10.20307/nps.2020.26.3.183
Genome mining has recently emerged as a powerful strategy to discover novel microbial secondary metabolites. However, more than 50% of biosynthetic gene clusters are not transcribed under standardized laboratory culture... -
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- Anti-adipogenic Pregnane Steroid from a Hydractinia-associated Fungus, Cladosporium sphaerospermum SW67
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Lee SR, Kang H, Yoo MJ, Yi SA, Beemelmanns C, Lee J, Kim KH
- KMID: 2507460
- Nat Prod Sci.
- 2020 Sep;26(3):230-235.
- doi: 10.20307/nps.2020.26.3.230
A pregnane steroid, 3α-hydroxy-pregn-7-ene-6,20-dione (1), was isolated from a Hydractinia-associated Cladosporium sphaerospermum SW67 by repetitive column chromatographic separation and highperformance liquid chromatography (HPLC) purification. The planar structure of 1 was... -
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- Isolation of Phytochemicals from Salvia plebeia Using Countercurrent Chromatography Coupled with Reversed-phase HPLC
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Kil HW, Rho T, Seo YJ, Yu A, Yoon KD
- KMID: 2507461
- Nat Prod Sci.
- 2020 Sep;26(3):236-243.
- doi: 10.20307/nps.2020.26.3.236
Salvia plebeia R. Br. is a plant which has been used as an edible crop and traditional medicine in Asian countries. In this study, HPLC-PDA analysis and countercurrent chromatography (CCC)... -
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- Fucoidan Induces Apoptosis in A2058 Cells through ROS-exposed Activation of MAPKs Signaling Pathway
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Ryu YS, Hyun JW, Chung HS
- KMID: 2507448
- Nat Prod Sci.
- 2020 Sep;26(3):191-199.
- doi: 10.20307/nps.2020.26.3.191
Fucoidan, a natural component of brown seaweed, has various biological activities such as anticancer activity, anti-oxidant, and anti-inflammatory against various cancer cells. However, the fucoidan has been implicated in melanoma... -
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- Liver Function Analyses and Spleen Histology Assessment Following the Co-administration of Cisplatin and Methanolic Extract of Portulaca Oleracea in Wistar Rats: An Experimental Study
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Okafor IA, Nnamah US, Nnaka J
- KMID: 2507466
- Nat Prod Sci.
- 2020 Sep;26(3):252-258.
- doi: 10.20307/nps.2020.26.3.252
This study investigated the biochemical and histological changes associated with the co-administration of cisplatin and methanolic extract of Portulaca Oleracea (MEPO) in adult Wistar rats. Twenty-four (24) adult female Wistar... -
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- Anti-Inflammatory Effects of Fermented Products with Avena sativa on RAW264.7 and HT-29 Cells via Inhibition of Inflammatory Mediators
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Shin J, Lee M
- KMID: 2507464
- Nat Prod Sci.
- 2020 Sep;26(3):244-251.
- doi: 10.20307/nps.2020.26.3.244
This study investigated therapeutic candidates with anti-inflammatory potential among traditional dietary ingredients targeting inflammatory bowel disease (IBD). Both Avena sativa and traditional fermented products, such as Korean soy paste, are... -
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- Protective Effect of Rice Bran Oil against β-Amyloid Protein-Induced Memory Impairment and Neuronal Death in Mice
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Jang JY, Lee HK, Yoo HS, Seong YH
- KMID: 2507457
- Nat Prod Sci.
- 2020 Sep;26(3):221-229.
- doi: 10.20307/nps.2020.26.3.221
This study was undertaken to investigate the protective effect of rice bran oil (RBO) on amyloid β protein (Aβ) (25-35)-induced memory impairment and brain damage in an ICR mouse model.... -
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- Effects of Compounds from Physalis angulata on Fatty Acid Synthesis and Glucose Metabolism in HepG2 Cells via the AMP-activated Protein Kinase Pathway
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Hoa HT, Thu NT, Dong NT, Oanh TT, Hien TT, Ha DT
- KMID: 2507451
- Nat Prod Sci.
- 2020 Sep;26(3):200-206.
- doi: 10.20307/nps.2020.26.3.200
The ability of the total extract from Physalis angulata; three fractions after partitioning with n-hexane, ethyl acetate (TBE), and water; and four withanolides (compounds 1 – 4) to phosphorylate 5'-adenosine... -
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- Characterization and Potent Application of Pleurotus floridanus Trypsin Inhibitor (PfTI)
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Pannippara MA, Kesav S, Naduvil Raghavan RMK, Mathew A, Bhat SG, Kozhiyil EK
- KMID: 2507452
- Nat Prod Sci.
- 2020 Sep;26(3):207-213.
- doi: 10.20307/nps.2020.26.3.207
Characterization and in vitro inhibition studies of protease inhibitor from the mushroom Pleurotus floridanus (PfTI) towards the pest Papilio demoleus is studied. The addition of 1 mM Mn2+ , Na2+... -
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- Isolation and Identification of Bioactive Compounds from the Tuber of Brassica oleracea var. gongylodes
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Prajapati R, Seong SH, Kim HR, Jung HA, Choi JS
- KMID: 2507454
- Nat Prod Sci.
- 2020 Sep;26(3):214-220.
- doi: 10.20307/nps.2020.26.3.214
Brassica oleracea var. gongylodes (red kohlrabi) is a biennial herbaceous vegetable whose edible bulbotuber-like stem and leaves are consumed globally. Sliced red kohlrabi tubers were extracted using methanol and the... -
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