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Cardiac physiologic regulation of sub-type specific adrenergic receptors in transgenic mice overexpressing β₁- and β₂-adrenergic receptors

Kim KE, Tae HJ, Natalia P, Lee JC, Ahn JH, Park JH, Kim IH, Ohk TG, Park CW, Cho JH, Won MH

OBJECTIVE: Combination of β₁-adrenergic receptor (AR) blockade and β₂-AR activation might be a potential novel therapy for treating heart failure. However, use of β-AR agonists and/or antagonists in the clinical...
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Cardiac Physiologic Regulation of Sub-type Specific Adrenergic Receptors in Transgenic Mice Overexpressing β1- and β2-Adrenergic Receptors

Kim KE, Tae HJ, Natalia P, Lee JC, Ahn JH, Park JH, Kim IH, Ohk TG, Park CW, Cho JH, Won MH

PURPOSE: A combination of β1-adrenergic receptor (β₁-AR) blockade and β₂-AR activation might potentially be the novel therapy for treating heart failure. However, the use of β-AR agonists and/or antagonists in...
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