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Recurrence of pediatric cerebral arteriovenous malformation after obliteration by radiosurgery: a case report

Lee T, Nam D, Chang WS, Mun HY

The rupture of a cerebral arteriovenous malformation is the most common cause of cerebral hemorrhage in children, with recurrence rates reported to be higher than that in adults. Herein, we...
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Ultrasonographic assessment of experimentally induced gastric perforation in beagle dogs

The goals of this study were, first, to evaluate the feasibility of inducing gastric perforation with 99% alcohol injection after electrocautery (EA-method), and, second, to observe “enhanced peritoneal stripe sign...
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Performance Comparison of Two Gene Set Analysis Methods for Genome-wide Association Study Results: GSA-SNP vs i-GSEA4GWAS

Kwon JS, Kim J, Nam D, Kim S

Gene set analysis (GSA) is useful in interpreting a genome-wide association study (GWAS) result in terms of biological mechanism. We compared the performance of two different GSA implementations that accept...
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Rab GTPases as Physiological Substrates of LRRK2 Kinase

Seol W, Nam D, Son I

LRRK2 (Leucine-Rich Repeat Kinase 2) is a gene whose specific mutations cause Parkinson's disease (PD), the most common neurodegenerative movement disorder. LRRK2 harbors GTPase and kinase activities, two enzyme activities...
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Pathological Characteristics of Monosodium Iodoacetate-Induced Osteoarthritis in Rats

Kwon M, Nam D, Kim J

BACKGROUND: This study aimed to identify pain-related behavior and pathological characteristics of the knee joint in rats with monosodium iodoacetate (MIA)-induced osteoarthritis (OA). METHODS: Knee joint inflammation was induced by intra-articular...
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Efficacy of minimal invasive cardiac output and ScVOâ‚‚ monitoring during controlled hypotension for double-jaw surgery

Kim S, Song J, Ji S, Kwon MA, Nam D

BACKGROUND: Controlled hypotension (CH) provides a better surgical environment and reduces operative time. However, there are some risks related to organ hypoperfusion. The EV1000/FloTrac system can provide continuous cardiac output...
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Clinical significance of skin test and specific IgE measurement for the prediction of immediate type hypersensitivity reaction to horse antithymocyte globulin

Lee HJ, Yim EJ, Ji SY, Kang SY, Suh YJ, Cho JW, Kim SS, Lee SK, Nahm DH, Park HS, Kim HS, Nam D, Kim HC

  • KMID: 1563756
  • J Asthma Allergy Clin Immunol.
  • 2000 Dec;20(6):936-942.
BACKGROUND: Horse antithymocyte globulin (ATG) is a useful treatment for aplastic anemia and for bone marrow transplantation from HLA-mismatched donors. Mortality due to anaphylactic reaction to horse ATG has been...
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Bioinformatics services for analyzing massive genomic datasets

Ko G, Kim PG, Cho Y, Jeong S, Kim JY, Kim KH, Lee HY, Han J, Yu N, Ham S, Jang I, Kang B, Shin S, Kim L, Lee SW, Nam D, Kim JF, Kim N, Kim SY, Lee S, Roh TY, Lee B

The explosive growth of next-generation sequencing data has resulted in ultra-large-scale datasets and ensuing computational problems. In Korea, the amount of genomic data has been increasing rapidly in the recent...
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Ciliogenesis is Not Directly Regulated by LRRK2 Kinase Activity in Neurons

Kim H, Sim H, Lee JE, Seo MK, Lim J, Bang Y, Nam D, Lee SY, Chung SK, Choi HJ, Park SW, Son I, Kim J, Seol W

  • KMID: 2517476
  • Exp Neurobiol.
  • 2021 Jun;30(3):232-243.
  • doi: 10.5607/en21003
Mutations in the Leucine-rich repeat kinase 2 (LRRK2 ) gene are the most prevalent cause of familial Parkinson’s disease (PD). The increase in LRRK2 kinase activity observed in the pathogenic...
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