- Craniofacial morphologic alteration induced by bone-targeted mutants of FGFR2 causing Apert and Crouzon syndrome
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Lee KJ, Nah HD, Tjoa ST, Park YC, Baik HS, Yun TM, Song JW
- KMID: 2273587
- Korean J Orthod.
- 2006 Aug;36(4):284-294.
OBJECTIVE: Activating mutations in the fibroblast growth factor receptor-2 (FGFR2) have been shown to cause syndromic craniosynostosis such as Apert and Crouzon syndromes. The purpose of this pilot study was... -
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- Generation of a transgenic mouse model to study cranial suture development; Apert syndrome
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Lee KJ, Ratisoontorn C, Baik HS, Park YC, Park KK, Nah HD
- KMID: 1976478
- Korean J Orthod.
- 2003 Dec;33(6):485-497.
The form and function of the craniofacial structure critically depend on genetic information. With recent advances in the molecular technology, genes that are important for normal growth and morphogenesis of... -
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