- Postnatal Development of Activities of MFO in Hepatic Microsomes from Rats Treated with Alcohol
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Kim KH
- KMID: 2052641
- Ewha Med J.
- 1991 Sep;14(3):223-228.
- doi: 10.12771/emj.1991.14.3.223
General concepts of hepatic drug-metabolizing enzymes in liver microsomes and the characteristics of induction of the enzyme are well known in adult rats. However there are few detailed reports on... -
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- Studies on Activities of Xenobiotic Metabolic Enzymes in Rats treated with Trichloroethylene
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Kim KW, Kang SK, Choi BS, Lee JS, Kim JS, Moon YH
- KMID: 2074949
- Korean J Occup Environ Med.
- 1994 Sep;6(2):323-331.
Trichloroethylene (TRI) is one of the most widely used organic solvent in many industries. It is used a degreasing agent, extract and dillution solvents. TRI is metabolized by liver microsomal... -
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- Cytochrome P-450, Drug Metabolizing Enzymes and Arachidonic Acid Metabolism in Pig Ocular Tissues
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Lee HR, Choi KR, Cho BC
- KMID: 2205166
- J Korean Ophthalmol Soc.
- 1995 Dec;36(12):2095-2107.
The eye is a relatively isolated organ and tends to retain or accumulate compounds within itself. Unless the eye possesses a mechanism for detoxifying drugs and chemicals that are carried... -
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- Preventive Effects of Chitosan on the Disorders of Hepatic Functions and Lipid Metabolism in Rats Treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
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Lee JH, Hwang SY, Lee YS
- KMID: 2269904
- Korean J Nutr.
- 2005 Nov;38(9):689-697.
This study was conducted to fine out the preventive effects of chitosan and chitosan oligomer on the disorders of hepatic functions and lipid metabolism induced by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin... -
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- Induction of Hepatic Microsomal Cytochrome P450 by N,N-dimethylformamide in Sprague-Dawley Rats
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Koh SB, Cha BS, Kim KJ, Kang SK, Joung HS
- KMID: 2282984
- Korean J Prev Med.
- 1999 Feb;32(1):88-94.
OBJECTIVES: In order to gain a better understanding of the mechanism of DMF toxicity, recent studies have focused on hepatic drug metabolizing enzymes. In this study, we investigated the effects... -
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- Dehydroepiandrosterone supplement increases malate dehydrogenase activity and decreases NADPH-dependent antioxidant enzyme activity in rat hepatocellular carcinogenesis
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Kim J, Kim SH, Choi H
- KMID: 2313354
- Nutr Res Pract.
- 2008 Jun;2(2):80-84.
Beneficial effects of dehydroepiandrosterone (DHEA) supplement on age-associated chronic diseases such as cancer, cardiovascular disease, insulin resistance and diabetes, have been reported. However, its mechanism of action in hepatocellular carcinoma... -
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- DNA Microarray Analysis of Transcriptional Responses in HepG2 Cells with Induced Paraquat Resistance
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Kim H, Lee SW, Kim SW
- KMID: 2332440
- J Korean Soc Emerg Med.
- 2008 Jun;19(3):322-332.
PURPOSE: To date, paraquat poisoning has almost universally resulted in unfavorable outcomes, and it has become a big issue in clinical toxicology. Current efforts to overcome its toxicity have focused... -
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- Effects of Ischemia/Reperfusion on Hepatic Secretion and Microsomal Drug- Metabolism in rat
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Cho JP, Jung YS
- KMID: 2100503
- J Korean Soc Emerg Med.
- 1997 Dec;8(4):479-489.
Ischemia causes tissue necrosis in a wide variety of pathologic conditions. Permanent deprivation of blood flow is lethal to any tissue and the prudent therapy for ischemia unquestionably is reperfusion.... -
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