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Anti-inflammatory effects of IL-4 and IL-10 on Human Polymorphonuclear Leukocytes

Lee SW, Hong YS, Chun CM, Moon JD, Kim SJ, Jung IC, Yoon YH, Lee BA, Moon SW, Choi SH, Moon CK

Inflammatory responses are strictly regulated by coordination of pro-inflammatory and anti-inflammatory mediators. Interleukin-4 (IL-4) and interleukin-10 (IL-10) have typically the biologic anti-inflammatory effects on monocytes, but uncertain effects on polymorphonuclear...
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Calyculin A modulates activation of the NADPH-oxidase in Me2SO-differentiated HL-60 cells

Park JI, Uhlinger D, Chung BS, Kim IH, Kwak JY

  • KMID: 755011
  • Exp Mol Med.
  • 1998 Dec;30(4):214-220.
Human promyelocytic leukemia cells (HL-60) have been used as a model system in which to study the effects of protein phosphatase inhibitors on NADPH-oxidase activation. Since O2- is generated by...
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In vitro Model System of Transepithelial Migration of Neutrophil by Helicobacter pylori

Jung HC, Kim JG, Kim JM, Song IS, Park SM

  • KMID: 772517
  • Korean J Gastroenterol.
  • 2003 Jul;42(1):20-26.
BACKGROUND/AIMS: Migration of neutrophil across the intestinal epithelium is a structural hallmark of active intestinal diseases. One of the characteristic histologic features of Helicobacter pylori (H. pylori) infection is...
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Chemotaxis of Blood Neutrophils from Patients with Primary Ciliary Dyskinesia

Koh YY, Sun YH, Min YG, Chi JG, Kim CK

Primary ciliary dyskinesia is characterized by chronic upper and lower respiratory infections which are caused by the grossly impaired ciliary transport. Since the cilia and neutrophils both utilize microtubular system...
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