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Inhibition of Janus activated kinase-3 protects against myocardial ischemia and reperfusion injury in mice

Oh YB, Ahn M, Lee SM, Koh HW, Lee SH, Kim SH, Park BH

  • KMID: 2154242
  • Exp Mol Med.
  • 2013 May;45(5):e23.
Recent studies have documented that Janus-activated kinase (JAK)-signal transducer and activator of transcription (STAT) pathway can modulate the apoptotic program in a myocardial ischemia/reperfusion (I/R) model. To date, however, limited...
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Infarct Size-limiting Effect of Calcium Preconditioning in Rabbit Hearts

Kim HD

Recent studies demonstrated that brief period of Ca2+ depletion and repletion (Ca2+ preconditioning, CPC) has strong protective effects against ischemia in a rat heart. CPC and classic preconditioning (IPC) were...
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