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Macrophage Apoptosis in Tuberculosis

Lee J, Hartman M, Kornfeld H

Mycobacterium tuberculosis (Mtb) is an intracellular pathogen that infects alveolar macrophages following aerosol transmission. Lung macrophages provide a critical intracellular niche that is required for Mtb to establish infection in...
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Immunological Mechanisms by Which Concomitant Helminth Infections Predispose to the Development of Human Tuberculosis

Mendez-Samperio P

  • KMID: 1792119
  • Korean J Parasitol.
  • 2012 Dec;50(4):281-286.
Helminthic infections afflict over 1.5 billion people worldwide, while Mycobacterium tuberculosis infects one third of the world's population, resulting in 2 million deaths per year. Although tuberculosis and helminthic infections...
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Development of a Quantitative Sandwich Enzyme-Linked Immunosorbent Assay for Detecting the MPT64 Antigen of Mycobacterium tuberculosis

Ji M, Cho B, Cho YS, Park SY, Cho SN, Jeon BY, Yoon BS

PURPOSE: Tuberculosis (TB) is a major infectious disease and is responsible for two million deaths annually. For the identification and quantitation of Mycobacterium tuberculosis (M. tuberculosis), a causative agent of...
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Isolation of perchloric acid soluble, heat stable, ethanol extractable protein from Mycobacterium tuberculosis

Kim DS, Han BH, Lee KY

The perchloric acid soluble, heat stable, and ethanol insoluble antigen of M. tuberculosis (TB-PBE) was prepared, and antigenicity of this antigen was studied in vivo and in vitro. TB-PBE showed...
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Production of monoclonal antibodies to lipoarabinomannan-B and use in the detection of mycobacterial antigens in sputum

Cho SN, Shin JS, Kim JD, Chong Y

Tuberculosis has traditionally been confirmed by AFB staining or culturing Mycobacterium tuberculosis from clinical specimens. However, because of the low sensitivity of the sputum smear examination and of the delayed...
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Prevalence of Antibodies to PPD and Lipoarabinomannan of Mycobacterium tuberculosis among Patients with an Indication of Fine Needle Aspiration Biopsy

Cho SN, Choi BW, Ra SY, Hong YK, Park JS, Kim SC, Kim JD, Choe KO

Recent increase in the incidence of lung cancer often makes it difficult to differentiate between lung cancer and tuberculosis (TB), due to their radiologic similarities. Fine needle aspiration biopsy (FNAB)...
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