- Stereoselective Microbial Hydroxylation of Progestin, Norethisterone by Using Aspergillus niger and Penicillium citrinum
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A, Iqbal M, Musharraf SG, Shahzad S
- KMID: 2511946
- Nat Prod Sci.
- 2020 Dec;26(4):283-288.
- doi: 10.20307/nps.2020.26.4.283
Microbial transformation of a potent progestin, norethisterone (17β-hydroxy-19-nor-17α-pregn-4-en-20-yn-3-one) (1) was carried out by using two filamentous fungi Aspergillus niger and Penicillium citrinum. Biotransformation of 1 with A. niger yielded a hydroxylated... -
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