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Leukemia propagating cells in Philadelphia chromosome-positive ALL: a resistant phenotype with an adverse prognosis

El-Menshawy N, Abd-Aziz S, Elkhamisy , Ebrahim MA

BACKGROUND: Targeted therapy has revolutionized the management of Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL); however, relapse still occurs because of the presence of quiescent stem cells, termed leukemia propagating...
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The Therapeutic Effect of Human Embryonic Stem Cell-Derived Multipotent Mesenchymal Stem Cells on Chemical-Induced Cystitis in Rats

Lee SW, Ryu CM, Shin JH, Choi D, Kim A, Yu HY, Han JY, Lee HY, Lim J, Kim YH, Heo J, Lee S, Ju H, Kim S, Hong KS, Han JY, Song M, Chung HM, Kim JK, Shin DM, Choo MS

PURPOSE: To evaluate the therapeutic effect of human embryonic stem cell (hESC)-derived multipotent mesenchymal stem cells (M-MSCs) on ketamine-induced cystitis (KC) in rats. METHODS: To induce KC, 10-week-old female rats were...
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Comparison of the characteristics of canine adipose tissue-derived mesenchymal stem cells extracted from different sites and at different passage numbers

Yaneselli , Kuhl CP, Terraciano PB, de Oliveira FS, Pizzato SB, Pazza K, Magrisso A, Torman V, Rial A, Moreno M, Llambí S, Cirne-Lima E, Maisonnave J

Mesenchymal stem cells (MSCs) have desirable characteristics for use in therapy in animal models and veterinary medicine, due to their capacity of inducing tissue regeneration and immunomodulation. The objective of...
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Current and Future Perspectives of Stem Cell Therapy in Dermatology

Prodinger , Reichelt J, Bauer JW, Laimer M

Stem cells are undifferentiated cells capable of generating, sustaining, and replacing terminally differentiated cells and tissues. They can be isolated from embryonic as well as almost all adult tissues including...
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Extensive characterization of feline intra-abdominal adipose-derived mesenchymal stem cells

Kim HR, Lee J, Byeon JS, Gu NY, Lee J, Cho IS, Cha SH

Mesenchymal stem cells (MSCs) isolated from various tissues have been well characterized for therapeutic application to clinical diseases. However, in contrast to MSCs from other animal species, the characteristics of...
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Attachment and Differentiation of Human Umbilical Cord Stem Cells on to the Tooth Root Surface with and without the Use of Fibroblast Growth Factor-An In Vitro Study

George JP, Chakravarty P, Chowdhary , Purushothama H, Rao JA

BACKGROUND AND OBJECTIVES: The purpose of this first of its kind study was to analyse the growth, development and attachment of cultured human umbilical cord stem cells alone or supplemented...
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The differentiation of human multipotent adult progenitor cells into hepatocyte-like cells induced by coculture with human hepatocyte line L02

Mu N, Liu HB, Meng QH, Du DW, Jiang Y, Hu HZ

PURPOSE: The aim of this study was to establish an in vitro method to purify human multipotent adult progenitor cells (hMAPCs) and assess their possible differentiation into hepatocytes by coculture...
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Vascular differentiation of multipotent spermatogonial stem cells derived from neonatal mouse testis

Im JE, Song SH, Kim JY, Kim KL, Baek SH, Lee DR, Suh W

We previously reported the successful establishment of embryonic stem cell (ESC)-like multipotent spermatogonial stem cells (mSSCs) from neonatal mouse testis. Here, we examined the ability of mSSCs to differentiate into...
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Stem Cell Properties of Therapeutic Potential

Seo GS

Stem cell research is a innovative technology that focuses on using undifferentiated cells able to self-renew through the asymmetrical or symmetrical divisions. Three types of stem cells have been studied...
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Establishment and Characterization of Multipotent Germ Line Stem Cells (MGSCs) from Neonatal Mouse Testis

Han SC, Song H, Jun JH

  • KMID: 1483347
  • Korean J Reprod Med.
  • 2008 Mar;35(1):39-48.
OBJECTIVE: The aim of this study was to investigate whether multipotent germline stem cells (MGSCs) can be established from neonatal mouse testis. METHODS: Various cells containing MGSCs were collected from neonatal...
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