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Additional cytogenetic aberrations in chronic myeloid leukemia: a single-center experience in the Middle East

Safaei A, Monabati A, Safavi M, Atashabparvar A, Hosseini M

BACKGROUND: Additional cytogenetic aberrations are associated with disease progression in chronic myeloid leukemia (CML). This study was conducted to determine the type and frequency of these aberrations and their relationship...
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Overexpression of indoleamine 2,3-dioxygenase correlates with regulatory T cell phenotype in acute myeloid leukemia patients with normal karyotype

Arandi N, Ramzi M, Safaei F, Monabati A

BACKGROUND: Production of immunosuppressive enzymes such as indoleamine 2,3-dioxygenase (IDO) is one of the strategies employed by hematologic malignancies, including acute myeloid leukemia (AML), to circumvent immune surveillance. Moreover, IDO...
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