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Regulatory Roles of MAPK Phosphatases in Cancer

Low HB, Zhang Y

The mitogen-activated protein kinases (MAPKs) are key regulators of cell growth and survival in physiological and pathological processes. Aberrant MAPK signaling plays a critical role in the development and progression...
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Role of Extracellular Signal-Regulated Kinase 1/2 and Reactive Oxygen Species in Toll-Like Receptor 2-Mediated Dual-Specificity Phosphatase 4 Expression

Kim SY, Baek SH

  • KMID: 2320038
  • Yeungnam Univ J Med.
  • 2013 Jun;30(1):10-16.
BACKGROUND: Toll-like receptors (TLRs) are well-known pattern recognition receptors. Among the 13 TLRs, TLR2 is the most known receptor for immune response. It activates mitogen-activated protein kinases (MAPKs), which are...
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