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PKC alpha induces differentiation through ERK1/2 phosphorylation in mouse keratinocytes

Seo HR, Kwan YW, Cho CK, Bae S, Lee SJ, Soh JW, Chung HY, Lee YS

  • KMID: 1094073
  • Exp Mol Med.
  • 2004 Aug;36(4):292-299.
Epidermal keratinocyte differentiation is a tightly regulated stepwise process that requires protein kinase C (PKC) activation. Studies on cultured mouse keraitnocytes induced to differentiate with Ca2+ have indirectly implicated the...
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Calcitonin induces connective tissue growth factor through ERK1/2 signaling in renal tubular cells

Nakamura M, Ozaki T, Ishii A, Konishi M, Tsubota Y, Furui T, Tsuda H, Mori I, Ota K, Kakudo K

Calcitonin (CT), a polypeptide hormone, plays important roles in a variety of physiological processes. CT has been used clinically to treat osteoporosis and humoral hypercalcemia of malignancy. In order to...
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