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Improvement of Pregnancy Rate in Preimplantation Genetic Diagnosis with FISH Procedure by the Laboratory Optimization and Experiences

Lim CK, Min DM, Lee HS, Byun HK, Park SY, Ryu HM, Kim JY, Koong MK, Kang IS, Jun JH

  • KMID: 1891198
  • Korean J Fertil Steril.
  • 2004 Mar;31(1):29-39.
OBJECTIVES: This study was performed to evaluate the laboratory system for successful PGD using fluorescence in situ hybridization (FISH) and the clinical outcome of PGD cycles in five years experiences. METHODS:...
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Development of an Efficient Method for Obtaining Metaphase Chromosomes in Individual Blastomeres of Mouse and Human Preimplantaion Embryos: Effect of Microtubule Depolymerizing Agents

Lim CK, Min DM, Lee HS, Kim JY, Koong MK, Kang IS, Jun JH

  • KMID: 1979046
  • Korean J Fertil Steril.
  • 2003 Jun;30(2):111-118.
OBJECTIVES: The development of an useful method for obtaining metaphase chromosomes from a biopsied blastomere would allow differentiation between embryos with balanced and normal chromosome complements in the preimplantation genetic...
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Outcome of Preimplantation Genetic Diagnosis for Chromosome Aneuploidy and Genetic Disease

Kim JY, Lim CK, Song IO, Yoo KJ, Yang KM, Han KS, Hur K, Song JH, Jun JH, Min DM, Park SY, Jun JY, Koong MK, Kang IS

  • KMID: 1566323
  • Korean J Fertil Steril.
  • 2002 Dec;29(4):269-278.
OBJECTIVES: Chromosome aneuploidy is associated with recurrent abortion and congenital anomaly and genetic diseases occur repeatedly in the specific families. Preimplantation genetic diagnosis (PGD) can prevent aneuploidy or genetic disease...
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Successful Preimplantation Genetic Diagnosis for Ornithine Transcarbamylase Deficiency, Junctional Epidermolysis Bullosa and Lactic Acidosis Using Duplex Nested PCR: Delivery of Healthy Baby by Specific Preimplantation Genetic Diagnosis for Ornithine Tran

Lee HS, Choi HW, Lim CK, Min DM, Byun HK, Kim JY, Koong MK, Yoo HW, Kim SC, Jun JH, Kang IS

  • KMID: 2272309
  • Korean J Obstet Gynecol.
  • 2004 Apr;47(4):708-718.
OBJECTIVE: Preimplantation genetic diagnosis (PGD) is reserved for couples with a risk of transmitting a serious and incurable disease, and hence avoids the undesirable therapeutic abortion. Herein, we report the...
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