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Complexity of the Diagnosis of COVID-19 in the Context of Pandemicity: Need for Excellence in Diagnostic Acumen

Joishy SK, Sadohara M, Kurihara M, Tokuda Y

Coronavirus disease 2019 (COVID-19) is a highly infectious disease that has caused a pandemic devastating many countries worldwide. It is a complex and multifaceted disease with a unique coronavirus etiology,...
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Evaluation of Hospital Avoidance at Department of Hand Surgery in Tertiary Hospital after Infectious Disease Outbreaks

Lee SH, Shin HD, Cha SM, Choi ES

Purpose: To compare the impact of hospital avoidance on the department of hand surgery at a tertiary hospital in Daejeon in the wake of the Middle East respiratory syndrome (MERS-CoV)...
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The role of lipids in the pathophysiology of coronavirus infections

Zandi M, Hosseini P, Soltani S, Rasooli A, Moghadami M, Nasimzadeh S, Behnezhad F

Coronaviruses, which have been known to cause diseases in animals since the 1930s, utilize cellular components during their replication cycle. Lipids play important roles in viral infection, as coronaviruses target...
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Comparison of characteristics and ventilatory course between coronavirus disease 2019 and Middle East respiratory syndrome patients with acute respiratory distress syndrome

Khalid I, Yamani RM, Imran M, Akhtar MA, Imran M, Gul R, Khalid TJ, Wali GY

Background: Both coronavirus disease 2019 (COVID-19) and middle east respiratory syndrome (MERS) can cause acute respiratory distress syndrome (ARDS); however, the former is postulated to lead to an atypical ARDS...
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How lessons learned from the 2015 Middle East respiratory syndrome outbreak affected the response to coronavirus disease 2019 in the Republic of Korea

Yang TU, Noh JY, Song JY, Cheong HJ, Kim WJ

The Republic of Korea (ROK) experienced a public health crisis due to Middle East respiratory syndrome (MERS) in 2015 and is currently going through the coronavirus disease 2019 (COVID-19) pandemic....
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Associations Between General Perceptions of COVID-19 and Posttraumatic Stress Disorder in Korean Hospital Workers: Effect Modification by Previous Middle East Respiratory Syndrome Coronavirus Experience and Occupational Type

Lee Y, Kim K, Park S, Jung SJ

Objectives: This study investigated associations between perceptions of coronavirus disease 2019 (COVID-19) and the prevalence of posttraumatic stress disorder (PTSD) in workers at hospitals designated to treat COVID-19, as well...
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A Comprehensive Review of Coronavirus Disease 2019: Epidemiology, Transmission, Risk Factors, and International Responses

Li H, Burm SW, Hong SH, Ghayda RA, Kronbichler A, Smith L, Koyanagi A, Jacob L, Lee KH, Shin JI

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused a worldwide pandemic. The first reports of patients with COVID-19 were provided to World Health...
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Novel respiratory infectious diseases in Korea

Kim HJ

Respiratory infections are very common and highly contagious. Respiratory infectious diseases affect not only the person infected but also the family members and the society. As medical sciences advance, several...
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Computational Analysis of CoV-2, Severe Acute Respiratory Syndrome CoV & Middle East Respiratory Syndrome Genome using MEGA

Sohpal VK

The novel coronavirus pandemic that has originated from China and spread throughout the world in three months. Genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) predecessor, severe acute respiratory...
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Factors Associated with Burnout among Healthcare Workers during an Outbreak of MERS

Seo YE, Kim HC, Yoo SY, Lee KU, Lee HW, Lee SH

Objective Although healthcare workers (HCWs) experienced significant stress during the 2015 outbreak of Middle East Respiratory Syndrome (MERS), the factors associated with this stress remain unknown. Thus, the present study...
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Psychiatric Morbidity of Survivors One Year after the Outbreak of Middle East Respiratory Syndrome in Korea, 2015

Shin J, Park HY, Kim JL, Lee JJ, Lee H, Lee SH, Shin HS

OBJECTIVES: Patients with an infectious diseases during an outbreak can experience extreme fear and traumatic events in addition to suffering from their medical illness. This study examined the long-term impact...
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Impact of the 2015 Middle East Respiratory Syndrome Outbreak on Emergency Care Utilization and Mortality in South Korea

Lee SY, Khang YH, Lim HK

PURPOSE: In May 2015, South Korea experienced an epidemic of Middle East respiratory syndrome (MERS). This study investigated the impacts of MERS epidemic on emergency care utilization and mortality in...
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Influence of Fear about Middle East Respiratory Syndrome Event of Hospital Worker and General Public on Socio-Psychological Health: Mediating Effect of Posttraumatic Stress

Kim S, Kim T, Choi M, Jeong J, Kwon H, Kim H, Kim B, Eun H

OBJECTIVE: The objective of this study is to determine the effects of fear of Middle East respiratory syndrome (MERS) on socio-psychological health during an outbreak of MERS and the post-traumatic...
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Evolutionary relationship analysis of Middle East respiratory syndrome coronavirus 4a and 4b protein coding sequences

Kim JI, Park S, Bae JY, Park MS

The 4a and 4b proteins of the Middle East respiratory syndrome coronavirus (MERS-CoV) have been described for their antagonism on host innate immunity. However, unlike clustering patterns of the complete...
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Absence of neutralizing activity in serum 1 year after successful treatment with antivirals and recovery from MERS in South Korea

Choi JY, Oh JO, Ahn JY, Choi H, Kim JH, Seong H, Jeong SJ, Ku NS, Yeom JS, Choi JP

We evaluated the neutralizing activity in serum from three patients >1 year after recovery from Middle East respiratory syndrome (MERS) associated with mild pneumonia treated with antivirals during the MERS...
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Depression as a Mediator of Chronic Fatigue and Post-Traumatic Stress Symptoms in Middle East Respiratory Syndrome Survivors

Lee SH, Shin HS, Park HY, Kim JL, Lee JJ, Lee H, Won SD, Han W

OBJECTIVE: The relationship among chronic fatigue, depressive symptoms, and post-traumatic stress symptoms (PTSSs) among Middle East respiratory syndrome (MERS) survivors is poorly understood. METHODS: Of 148 survivors who consented to be...
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Correlation between Knowledge, Attitude, and Compliance of Preventive Behaviors regarding Middle East Respiratory Syndrome among Nursing Students

Park JH, Chang SJ, Choi S

PURPOSE: This study aimed to investigate the relationships between the level of knowledge, attitude and compliance of preventive behaviors of the Middle East respiratory syndrome (MERS) among nursing students. METHODS: The...
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Psychiatric Findings in Suspected and Confirmed Middle East Respiratory Syndrome Patients Quarantined in Hospital: A Retrospective Chart Analysis

Kim HC, Yoo SY, Lee BH, Lee SH, Shin HS

OBJECTIVE: Little is known about the psychiatric complications or risk factors for depression in suspected or confirmed Middle East Respiratory Syndrome (MERS) patients quarantined in hospital. METHODS: A retrospective chart review...
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Elementary, Middle, and High School Health Teachers' Countermeasures Against an Outbreak of Pandemic Diseases, Including MERS

Jun E, Lee G

PURPOSE: This study aims to examine how elementary, middle and high school health teachers in Gyeonggi province react to infectious disease like MERS. METHODS: This is a descriptive study using a...
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Middle East respiratory syndrome: what we learned from the 2015 outbreak in the Republic of Korea

Oh MD, Park WB, Park SW, Choe PG, Bang JH, Song KH, Kim ES, Kim HB, Kim NJ

Middle East Respiratory Syndrome coronavirus (MERS-CoV) was first isolated from a patient with severe pneumonia in 2012. The 2015 Korea outbreak of MERSCoV involved 186 cases, including 38 fatalities. A...
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