- The Effect of Lovastatin(Mevacor(R)) in Patients with Hypercholesterolemia
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Lee SY, Kyoung CS, Kim DC, Lee KH, Choi SJ, Son I, Park SH
- KMID: 2093279
- Korean Circ J.
- 1991 Apr;21(2):328-336.
- doi: 10.4070/kcj.1991.21.2.328
Lovastatin is a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, which catalyzes the conversion of hydroxymethylglutaryl-coenzyme A to mevalonate, anearly and rate-limiting step in the synthesis of cholesterol. We studied... -
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- Novel non-apoptotic cell death: ferroptosis
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Woo SM, Kwon TK
- KMID: 2400352
- Yeungnam Univ J Med.
- 2017 Dec;34(2):174-181.
- doi: 10.12701/yujm.2017.34.2.174
Ferroptosis is a newly recognized type of cell death that results from iron-dependent lipid peroxidation and is different from other types of cell death, such as apoptosis, necrosis, and autophagic... -
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- Antiproliferative Effect of Lovastatin on Vascular Smooth Muscle Cell
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Park SW, Kim DK, Huh JE, Choi YH, Choi YH, Gwon HC, Kim JS, Lee SH, Hong KP, Park JE, Seo JD, Lee WR
- KMID: 1858312
- Korean Circ J.
- 1998 Dec;28(12):1981-1992.
- doi: 10.4070/kcj.1998.28.12.1981
BACKGROUND AND OBJECTIVES: This study was performed to investigate the antiproliferative effect of lovastatin on vascular smooth muscle cell, especially to determine whether lovastatin induces apoptosis in vascular smooth muscle... -
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- Effects of Bisphosphonates on Glucose Transport in a Conditionally Immortalized Rat Retinal Capillary Endothelial Cell Line (TR-iBRB Cells)
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Lee NY, Park HJ, Kang YS
- KMID: 2170546
- Biomol Ther.
- 2016 Jan;24(1):94-98.
- doi: 10.4062/biomolther.2015.183
The objective of the present study was to elucidate the effect of bisphosphonates, anti-osteoporosis agents, on glucose uptake in retinal capillary endothelial cells under normal and high glucose conditions. The... -
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- HMG CoA Reductase Inhibitors Inhibit HCV RNA Replication of HCV Genotype 1b but Not 2a
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Chang KS, Jo HJ
- KMID: 2168627
- J Bacteriol Virol.
- 2011 Jun;41(2):99-108.
- doi: 10.4167/jbv.2011.41.2.99
Replication of hepatitis C virus (HCV) is regulated by statin, one of 3-hydroxy-3-methylglutaryl CoA reducatase (HMG CoA reductase) inhibitors that block mevalonate pathway and cholesterol biosyntheis, which has been used... -
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- Heterogeneity of Human γδ T Cells and Their Role in Cancer Immunity
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Lee HW, Chung YS, Kim TJ
- KMID: 2471045
- Immune Netw.
- 2020 Feb;20(1):e5.
- doi: 10.4110/in.2020.20.e5
The γδ T cells are unconventional lymphocytes that function in both innate and adaptive immune responses against various intracellular and infectious stresses. The γδ T cells can be exploited as... -
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- Dental Considerations of the Bisphosphonate-related Osteonecrosis of the Jaw
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Lee JK
- KMID: 2314086
- Osteoporosis.
- 2011 Apr;9(1):18-27.
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a disease entity which is rare, but is a serious side effect of bisphosphonate therapy. Several professional associations have published position papers on... -
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