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Effect of a Carcinogen, 3'-Methyl-4-Dimethylaminoazobenzene on Histopathological Changes of the Liver in Rats Experimentally Infected with Clonorchis sinensis

Min HK

Wistar rats were used and divided into 3 groups ; group I treated with 0.03% 3'MeDAB alone far 12 weeks, group II given 50 Clonorchis metacercariae alone and group III...
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Factors Influencing the Pathogenicity of Entamoeba Histolytica

Soh CT

In summarizing the results of the experimental studies up to the present, it is conjectured that the pathogenicity of Entamoeba histolytica or establishment of amoebiasis is not unique but differs...
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Surface Properties of Cell Membrane in Early Stage of Transformed Cell -I. Early Detection of Transformed Cell by Concanavalin A; II. Properties of Plasma Membrane of Transformed Rat Liver Cell Induced by 3'-Me DAB

Kim YS, Cho MY

The present study was designed in order to investigate the lectin induced cytoagglutination properties of normal and transformed cells and surface alterations in the early stage of the transformed cells...
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Expressions of c-fos and c-myc genes during 3'-methyl-4-dimethylaminoazobenzene (3'-MeDAB)-induced rat hepatocarcinoma

Chai KJ, Kim JS, Lee HK

We investigated the expression of the growth-related nuclear proto-oncogenes, c-fos and c-myc, in early preneoplastic regions and tumor nodules of 3'-MeDAB induced rat hepatocarcinoma. To amplify the levels of these...
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A Study of the Regulation of the Glucose Transporter in the Plasma Membranes of Hepatoma Cells Induced by 3'-Me DAB

Ahn YH, Chai KJ, Kim SN, Kim YS

5'-nucelotidase and glucose-6-phosphatase are liver plasma and microsomal membranes markers and their respective activities were determined. In the liver homogenate, the activities of 5'-nucleotidase were 0.58 +/- 0.08 and 0.29...
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A study on the regulation of translocation of glucose transporters during hepatocarcinogenesis induced by 3'-Me DAB

Kim YS, Paik EM, Lee MS, Kim KS, Chai KJ, Ahn YH

The mechanism of glucose transported (GT) expression on the plasma membranes of hepatoma cells in rats induced by 3'-methyl-4-dimethylaminoazobenzene (3'-MeDAB) was studied. Cytochalasin B binding to plasma membrane fractions from...
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Characterization of Tumor Specific Antigens on the Plasma Membrane Surface of Rat Hepatomas lnduced by 3'-Me DAB and ldentification of the Common Tumor Specific Antigens from Rat Hepatomas lnduced by Different Chemical Hepatocarcinogens

Kim YS, Hahm KS, Kim KS, Lee NJ

Three different chemical carcinogens, 2-acetylaminofluorene (AAF), diethylnitrosamine(DENA), and 3'-methyl-4dimethylaminoazobenzene (3'-Me DAB) were used to induce hepatomas in rats. Plasma membrane surface proteins of normal rat liver cells and rat hepatomas...
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