Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

PUBLICATION DATE

29 results
Display

Prolonged semen incubation alters the biological characteristics of human spermatozoa

Beigi SAD, Khalili MA, Nabi A, Hosseini M, Sarcheshmeh AA, Sabour M

Objective: The present study assessed the biological characteristics of human spermatozoa at different time intervals (0, 1, 1.5, and 2 hours) after incubation at 37°C. Methods: Twenty-five normozoospermic semen samples were...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Transient Receptor Potential Canonical 4 and 5 Channel Antagonist ML204 Depolarized Pacemaker Potentials of Interstitial Cells of Cajal

Lee JH, Wu WH, Huang XY, Jun JY, Choi S

  • KMID: 2507118
  • J Neurogastroenterol Motil.
  • 2020 Oct;26(4):521-528.
  • doi: 10.5056/jnm20064
Background/Aims To investigate an effect of ML204 (an inhibitor of transient receptor potential canonical 4 and 5 [TRPC4/5] channels) on interstitial cells of Cajal (ICCs) and therefore determine whether TRPC4/5 channels...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effect of Cyclosporine A-induced Senescence on Cultured Human Corneal Endothelial Cells

Jang YK, Chung TY, Shin YJ

Purpose: To investigate the in vitro effect of cyclosporine A (CsA)-induced senescence on human corneal endothelial cells (HCECs). Methods: HCECs were cultured and incubated with 0-100 µM CsA. Senescence-associated β–galactosidase (SA-β-gal)...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Lithium Stabilizes the Mood of Bipolar Patients by Depolarizing the Neuronal Membrane Via Quantum Tunneling through the Sodium Channels

Qaswal AB

Objective: Lithium is used as first line in treating bipolar patients to stabilize their mood. However, the exact mechanism of lithium is not yet established. One of the proposed mechanisms...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
MiR-484 Protects Rat Myocardial Cells from Ischemia-Reperfusion Injury by Inhibiting Caspase-3 and Caspase-9 during Apoptosis

Liu H, Li S, Jiang W, Li Y

BACKGROUND AND OBJECTIVES: To reveal the detail mechanism of miR-484 on myocardial ischemia-reperfusion (MI/R) injury. METHODS: Rats model of MI/R injury was established based on control (Con; sham operate) group, ischemia-reperfusion...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Anti-tumor activity and mitochondrial stability of disulfiram in HL-60 cells

Disulfiram (DSF) is a member of the dithiocarbamate family that can bind copper. Recent studies have shown that DSF has anti-cancer activities, but the mechanism has not been clarified. Therefore,...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Cyanidin-3-glucoside inhibits amyloid β₂₅₋₃₅-induced neuronal cell death in cultured rat hippocampal neurons

Yang JS, Jeon S, Yoon KD, Yoon SH

Increasing evidence implicates changes in [Ca²⁺]i and oxidative stress as causative factors in amyloid beta (Aβ)-induced neuronal cell death. Cyanidin-3-glucoside (C3G), a component of anthocyanin, has been reported to protect...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Nobiletin attenuates neurotoxic mitochondrial calcium overload through K⁺ influx and ΔΨ(m) across mitochondrial inner membrane

Lee JH, Amarsanaa , Wu J, Jeon SC, Cui Y, Jung SC, Park DB, Kim SJ, Han SH, Kim HW, Rhyu IJ, Eun SY

Mitochondrial calcium overload is a crucial event in determining the fate of neuronal cell survival and death, implicated in pathogenesis of neurodegenerative diseases. One of the driving forces of calcium...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
A Novel Nicotinamide Adenine Dinucleotide Correction Method for Mitochondrial Ca2+ Measurement with FURA-2-FF in Single Permeabilized Ventricular Myocytes of Rat

Lee JH, Ha JM, Leem CH

Fura-2 analogs are ratiometric fluoroprobes that are widely used for the quantitative measurement of [Ca2+]. However, the dye usage is intrinsically limited, as the dyes require ultraviolet (UV) excitation, which...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Kinetin inhibits apoptosis of aging spleen cells induced by D-galactose in rats

Li M, Ouyang W, Wu X, Zheng Y, Wei Y, An L

Kinetin (Kn) is a cytokinin growth factor that exerts several anti-aging and antioxidant effects on cells and organs. To investigate the mechanism underlying apoptotic events in aging cells induced by...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Cyanidin-3-glucoside Inhibits ATP-induced Intracellular Free Ca2+ Concentration, ROS Formation and Mitochondrial Depolarization in PC12 Cells

Perveen S, Yang JS, Ha TJ, Yoon SH

Flavonoids have an ability to suppress various ion channels. We determined whether one of flavonoids, cyanidin-3-glucoside, affects adenosine 5'-triphosphate (ATP)-induced calcium signaling using digital imaging methods for intracellular free Ca2+...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Fucodiphlorethol G Purified from Ecklonia cava Suppresses Ultraviolet B Radiation-Induced Oxidative Stress and Cellular Damage

Kim KC, Piao MJ, Zheng J, Yao CW, Cha JW, Kumara MH, Han X, Kang HK, Lee NH, Hyun JW

  • KMID: 2170623
  • Biomol Ther.
  • 2014 Jul;22(4):301-307.
Fucodiphlorethol G (6'-[2,4-dihydroxy-6-(2,4,6-trihydroxyphenoxy)phenoxy]biphenyl-2,2',4,4',6-pentol) is a compound purified from Ecklonia cava, a brown alga that is widely distributed offshore of Jeju Island. This study investigated the protective effects of fucodiphlorethol G...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Mycophenolic acid mediated mitochondrial membrane potential transition change lead to T lymphocyte apoptosis

Choi SJ, Lee HK, Kim NH, Chung SY

PURPOSE: This study demonstrated that apoptosis induced by mycophenolic acid (MPA) is mediated by mitochondrial membrane potential transition (MPT) changes in Jurkat cells. METHODS: Cell viability and MPT changes were measured...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Hydroxydibenzoylmethane induces apoptosis through repressing ornithine decarboxylase in human promyelocytic leukemia HL-60 cells

Wang MF, Liao YF, Hung YC, Lin CL, Hour TC, Lue KH, Hung HC, Liu GY

Ornithine decarboxylase (ODC) is the rate-limiting enzyme in polyamine biosynthesis and a target for chemoprevention. Hydroxydibenzoylmethane (HDB), a derivative of dibenzoylmethane of licorice, is a promising chemopreventive agent. In this...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Electrophysiological Characteristics of Human Colon Circular Muscle

Choe EK, Ryoo SB, Moon SH, Moon JS, Park KJ

PURPOSE: Interstitial cells of Cajal (ICC) play a core function in colonic motility as a pacemaker by regulating the slow wave. We intended to investigate the electrophysiological characteristics of the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Mitochondrial Dysfunction and Apoptosis Related Gene Expression in A beta(25-35)-Treated Human Neuroblastoma Cell Line, SK-N-SH

Choi YS, Kim SH

  • KMID: 2338986
  • J Korean Geriatr Soc.
  • 2009 Sep;13(3):142-151.
BACKGROUND: Mitochondrial dysfunction plays an important role in Abeta-induced neuronal toxicity in Alzheimer's disease (AD). We measured the membrane potentials of mitochondria (delta psim) and assessed the genetic expressions of...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Synthesis of (4-[18F]Fluorophenyl)triphenylphosphonium as a Mitochondrial Voltage Sensor for PET

Kim DY, Yu KH, Bom HS, Min JJ

  • KMID: 1910722
  • Nucl Med Mol Imaging.
  • 2007 Dec;41(6):561-565.
PURPOSE: Lipophilic cations including tetraphenylphosphonium (TPP) salts penetrate the hydrophobic barriers of the plasma and mitochondrial membranes, resulting in accumulation in mitochondria in response to the negative inner transmembrane potentials....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Hydrogenosomal activity of Trichomonas vaginalis cultivated under different iron conditions

Kim YS, Song HO, Choi IH, Park SJ, Ryu JS

To evaluate whether iron concentration in TYM medium influence on hydrogenosomal enzyme gene expression and hydrogenosomal membrane potential of Trichomonas vaginalis, trophozoites were cultivated in irondepleted, normal and iron-supplemented TYM...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Study on the Mitochondrial Dysfunction by p53 Regulation in Ceramide-induced Neuronal Cell Death

Lee DY, Lee HJ, Noh YH, Yun JY, Han IS, Chung YH, Kim KY, Kim SS, Lee WB

  • KMID: 1512990
  • Korean J Phys Anthropol.
  • 2006 Mar;19(1):49-59.
Ceramide induces cell death in a dose- and time-dependent manner in neuroblastoma SK-N-SH cells. To investigate the mechanism of SK-N-SH cell death by C2-ceramide, morphological features and Hoechst 33258 staining...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Studies on Signal Transduction Mechanism of Alcohol-induced Neuronal Cell Death and Protective Effect

Lee DY, Kim SS, Kim KY, Lee WB, Kim DK, Kim KH, Jung HY, Lee SH

  • KMID: 1517132
  • Korean J Phys Anthropol.
  • 2004 Mar;17(1):31-43.
Excessive use of alcohol is a serious problem in our society and induces various, severe alcohol related diseases. The cytotoxicities of ethanol are still largely unknown. We studied the molecular...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2023 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr