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Is meconium exposure associated with autism spectrum disorders in children?

Jenabi E, Ayubi E, Khazaei S, Bashirian S, Khazaei M

Background: The results differ among published studies regarding exposure to meconium and the risk of developing autism spectrum disorders (ASDs). Purpose: The present study pooled all of the epidemiologic studies retrieved...
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Intussusception in Neonates: Clinical Characteristics of Eight Cases in a Single Center

Ahn Yg, Lim G, Hwang EH, Oh KW, Cho MJ

Purpose: Intussusception is the most common cause of bowel obstruction in children; however, it is rarely diagnosed in newborn infants. This study aimed to describe the clinical features of intussusception...
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Oral Administration of Nonionic Water-Soluble Contrast Media to Treat Meconium Obstruction in Premature Infants: A Preliminary Study

Hong HS, Kim SS, Park GY

Purpose: Meconium obstruction of prematurity (MOP) predisposes premature infants to intestinal perforation and prolonged hospitalization if not diagnosed and treated promptly. A standard contrast enema is less effective to treat...
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Waardenburg Syndrome Type IV De Novo SOX10 Variant Causing Chronic Intestinal Pseudo-Obstruction

Hogan AR, Rao KA, Thorson WL, Neville HL, Sola JE, Perez EA

Waardenburg syndrome (WS) type IV is characterized by pigmentary abnormalities, deafness and Hirschsprung's disease. This syndrome can be triggered by dysregulation of the SOX10 gene, which belongs to the SOX...
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Comparison of Acute Abdominal Surgical Outcomes of Extremely-Low-Birth-Weight Neonates according to Differential Diagnosis

Byun J, Kim HY, Jung SE, Yang HB, Kim EK, Shin SH, Kim HS

BACKGROUND: Improvements in perinatal intensive care have improved survival of extremely-low-birth-weight (ELBW) neonates, although the risk of acute abdomen has increased. The differential diagnosis resulting in abdominal surgery can be...
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A Case of a Patent Omphalomesenteric Duct Presenting with Meconium Discharge from the Umbilicus

Han CH, Son MW, Song JH

The omphalomesenteric duct is a link between the primitive midgut and the yolk sac. Normally, the duct obliterates around 6 weeks of gestation, yet varying degrees of incomplete obliteration can...
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Empirical Antibiotics in Non-Ventilated Cases of Meconium Aspiration Syndrome

Kang SM, Jo CK, Lee SY, Kim MJ

PURPOSE: Meconium aspiration is assumed to be a risk factor for bacterial infection, and patients with meconium aspiration syndrome (MAS) are commonly treated with empiric antibiotics in clinical settings. However,...
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Meconium Peritonitis: A Rare Treatable Cause of Non-Immune Hydrops

Rajendran , Govindarajan J, Balakrishnan U, Chandrasekaran A, Amboiram P

Meconium peritonitis as a cause of non-immune hydrops in neonates is rarely reported. Here we report such a rare occurrence. In our case, a routine antenatal scan at 25 weeks...
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Successful Ultrasound-Guided Gastrografin Enema for Very Low Birth Weight Infants with Meconium-Related Ileus

Shin J, Jeon GW

PURPOSE: Meconium-related ileus is common in preterm infants. Without proper management, it can cause necrotizing enterocolitis and perforation requiring emergent operation. This study was conducted to describe the efficacy and...
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Efficacy of Serum Neutrophil-to-Lymphocyte Ratio for Meconium Aspiration Syndrome

Jo CK, Kang SM, Lee SY, Kim MJ

OBJECTIVE: To evaluate the relationship between serum neutrophil-to-lymphocyte ratio (NLR) and severity of meconium aspiration syndrome (MAS). METHODS: We retrospectively analyzed 197 neonates who admitted for MAS between 2008 and 2016...
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Association of Fatty Acid Ethyl Esters in Meconium of Neonates with Growth Deficits at Birth: a Prospective, Single-Centre Cohort Study

Lee HS, Kim YH, Kwak HS, Han JY, Jo SJ, Lee HK

BACKGROUND: In this prospective cohort study, we investigated the association between fatty acid ethyl esters (FAEEs) in meconium as biomarkers of prenatal ethanol exposure and growth deficits, as birth outcomes,...
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Placental Lesions in Meconium Aspiration Syndrome

Kim B, Oh SY, Kim JS

BACKGROUND: Meconium aspiration syndrome (MAS) is defined by respiratory distress requiring supplemental oxygen in a meconium-stained neonate. MAS is clinically subclassified as mild, moderate, and severe according to the oxygen...
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Clinical Features and Outcomes of Perinatally Diagnosed Meconium Peritonitis

Koo EJ, Jung E, Choi SO, Bae JG

OBJECTIVE: Meconium peritonitis (MP) is defined as sterile chemical peritonitis, resulting from intrauterine bowel perforation. MP is rare but has high morbidity and mortality in neonates. We aimed to review...
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Meconium Aspiration Syndrome: The Core Concept of Pathophysiology during Resuscitation

Yeh TF

Aspiration of meconium produces a syndrome (Meconium Aspiration Syndrome MAS) characterized by hypoxia, hypercapnia, and acidosis. Perinatal hypoxia, acute airway obstruction, pulmonary inflammation, pulmonary vasoconstriction, pulmonary hypertension, and surfactant inactivation...
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Efficacy of Ultrasound-guided Contrast Enema on Meconium Plug Syndrome in Preterm Infants

Lee BK, Kim HR, Kim JY, Choi CW, Kim BI

PURPOSE: This study aims to compare the effectiveness and safety of ultrasound-guided contrast enema comparing with exploratory laparotomy for meconium plug syndrome in preterm infants. METHODS: Fifty-three preterm infants who were...
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Serum Enzymes in Predicting the Severity of Meconium Aspiration Syndrome in Newborn

Yang MY, Kim IU, Jeong HR, Kim SH, Kim DH, Kim HS

PURPOSE: Meconium aspiration syndrome (MAS), often progresses to respiratory failure and its' serious complication, persistent pulmonary hypertension of the newborn (PPHN) is a major cause of neonatal mortality. Early recognition...
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Meconium-related ileus in very low birth weight and extremely low birth weight infants: immediate and one-year postoperative outcomes

Kim HY, Kim SH, Cho YH, Byun SY, Han YM, Kim AY

PURPOSE: One of the major causes of bowel obstruction in extremely premature infants is a meconium obstruction. However, there are many challenges not only in the recognition and diagnosis, but...
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A Case of a Preterm Infant with Prenatally Diagnosed Intrauterine Midgut Volvulus

Woo HK, Lee HY, Kim SY, Jung YH, Shin SH, Kim HY, Kim EK, Kim HS, Jun JK, Choi JH

Intrauterine midgut volvulus is a rare and potentially life-threatening congenital disease that can lead to intestinal ischemia, sepsis and peritonitis caused by bowel perforation and meconium obstruction. Early detection and...
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Clinical Characteristics of Meconium Aspiration Syndrome according to Ventilator Care

Lim RK, Bae MH, Kim AY, Han YM, Park KH, Byun SY

PURPOSE: Meconium aspiration syndrome is an important cause of neonatal morbidity and mortality, and sometimes patients need mechanical ventilator therapy. The aim of this study was to identify the risk...
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Impact of Meconium Obstruction-Related Risk Factors on Surgical Intervention in Very Low Birth Weight Infants

Kwon HS, Jung JM, Lim YJ, Nam SH, Lim G, Chung ML

PURPOSE: This study investigated the risks of development and surgical complications of meconium obstruction (MO) in very low birth weight (VLBW) infants. METHODS: We performed a retrospective medical record review of...
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