- Proteostasis and Ribostasis Impairment as Common Cell Death Mechanisms in Neurodegenerative Diseases
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Lim SM, Nahm M, Kim SH
- KMID: 2539607
- J Clin Neurol.
- 2023 Mar;19(2):101-114.
- doi: 10.3988/jcn.2022.0379
The cellular homeostasis of proteins (proteostasis) and RNA metabolism (ribostasis) are essential for maintaining both the structure and function of the brain. However, aging, cellular stress conditions, and genetic contributions... -
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- Mitochondria in reproduction
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Kang MH, Kim YJ, Lee JH
- KMID: 2540241
- Clin Exp Reprod Med.
- 2023 Mar;50(1):1-11.
- doi: 10.5653/cerm.2022.05659
In reproduction, mitochondria produce bioenergy, help to synthesize biomolecules, and support the ovaries, oogenesis, and preimplantation embryos, thereby facilitating healthy live births. However, the regulatory mechanism of mitochondria in oocytes... -
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- Impact of Mechanism of Injury on Long-term Neurological Outcomes of Cervical Sensorimotor Complete Acute Traumatic Spinal Cord Injury
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Bak AB, Moghaddamjou A, Malvea A, Fehlings MG
- KMID: 2537370
- Neurospine.
- 2022 Dec;19(4):1049-1056.
- doi: 10.14245/ns.2244518.259
Objective: Mechanism of injury is a largely understudied descriptor of acute traumatic spinal cord injury (tSCI). This study sought to compare the impact of high-energy and low-energy mechanisms of injury... -
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- Senotherapeutics and Their Molecular Mechanism for Improving Aging
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Park J, Shin DW
- KMID: 2534698
- Biomol Ther.
- 2022 Nov;30(6):490-500.
- doi: 10.4062/biomolther.2022.114
Aging is defined as physiological dysfunction of the body and a key risk factor for human diseases. During the aging process, cellular senescence occurs in response to various extrinsic and... -
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- Comparison of Whole Spine Sagittal Alignment in Patients with Spinal Disease between EOS Imaging System versus Conventional Whole Spine X-ray
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Jang HJ, Park JY, Kuh SU, Ha Y, Chin DK, Kim KS, Cho YE, Kim KH
- KMID: 2536373
- Yonsei Med J.
- 2022 Nov;63(11):1027-1034.
- doi: 10.3349/ymj.2022.0023
Purpose: The biplanar whole body imaging system (EOS) is a new tool for measuring the whole body sagittal alignment in a limited space. This tool may affect the sagittal balance... -
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- Cisplatin-Induced Ototoxicity: Updates on Potential Molecular Mechanism
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Jung DJ
- KMID: 2534445
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2022 Oct;65(10):569-579.
- doi: 10.3342/kjorl-hns.2022.00507
Cis-diamminedichloroplatinum(II) (cisplatin), platinum compound, is an anti-cancer agent currently used for the treatment of a number of human solid cancers. It irreversibly reacts with DNA to form an interconnection between... -
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- Transdiagnostic Network Analysis Between Suicide Attempt and Personality, Defense Mechanism Factors in Neurotic Patients
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Jeong HM, Yun SH, Jo SH, Kim HG, Cheon EJ, Koo BH
- KMID: 2532254
- Psychoanalysis.
- 2022 Jul;33(3):45-55.
- doi: 10.18529/psychoanal.2022.33.3.45
Objectives: The purpose of this study is to investigate the complex relationship between personality characteristics, psychological characteristics, defense mechanisms, and suicide attempts in neurotic patients with frequent suicide attempts, such... -
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- High-on-Aspirin Platelet Reactivity Differs Between Recurrent Ischemic Stroke Associated With Extracranial and Intracranial Atherosclerosis
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Noh KC, Choi Hy, Woo HG, Chang JY, Heo SH, Chang Di, Kim BJ
- KMID: 2530844
- J Clin Neurol.
- 2022 Jul;18(4):421-427.
- doi: 10.3988/jcn.2022.18.4.421
Background and Purpose Ischemic stroke recurs despite the use of antiplatelet agents. Various mechanisms are involved in recurrence due to intracranial atherosclerosis (ICAS) and extracranial atherosclerosis (ECAS). High-on-aspirin platelet reactivity... -
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- Compensatory Pelvic Retro-Rotation Associated with a Decreased Quality of Life in Patients with Normal Sagittal Balance
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Shimokawa T, Miyamoto K, Hioki A, Masuda T, Fushimi K, Ogawa H, Ohnishi K, Akiyama H
- KMID: 2529530
- Asian Spine J.
- 2022 Apr;16(2):241-247.
- doi: 10.31616/asj.2020.0449
Study Design: Cross-sectional observational study. Purpose: To examine whether pelvic rotation as a compensatory mechanism for sagittal imbalance is related to quality of life (QOL). Overview of Literature: Poor sagittal alignment is... -
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- Vinyl-Stilbene Inhibits Human Norovirus RNA Replication by Activating Heat-Shock Factor-1
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Lee A, Sung J, Harmalkar DS, Kang H, Lee H, Lee K, Lee C
- KMID: 2524148
- Biomol Ther.
- 2022 Jan;30(1):64-71.
- doi: 10.4062/biomolther.2021.153
Norovirus (NV) is the most common cause of viral gastroenteritis, with the potential to develop into a fatal disease in those who are immuno-compromised, and effective vaccines and treatments are... -
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- Risks and management of hypertension in cancer patients undergoing targeted therapy: a review
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Zhu X, Wu S
- KMID: 2529745
- Clin Hypertens.
- 2022;28(1):14.
- doi: 10.1186/s40885-022-00197-3
Background: Rapid progress over the last decade has added numerous agents targeting specific cellular signaling pathways to the treatment armamentarium for advanced cancer. However, many of these agents can cause... -
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- The Roles of Human Endogenous Retroviruses (HERVs) in Inflammation
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Ko EJ, Cha HJ
- KMID: 2524669
- Kosin Med J.
- 2021 Dec;36(2):69-78.
- doi: 10.7180/kmj.2021.36.2.69
Human endogenous retroviruses (HERVs) are ancient, currently inactive, and non-infectious due to recombination, deletions, and mutations in the host genome. However, HERV-derived elements are involved in physiological phenomena including inflammatory... -
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- The Correlation Between Defense Mechanism and Posttraumatic Stress Disorder in Burn Patients
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Lee D, Choi Y, Kim JD, Son KL, Im WY, Jun JY
- KMID: 2524307
- Korean J Psychosom Med.
- 2021 Dec;29(2):191-198.
- doi: 10.22722/KJPM.2021.29.2.191
Objectives：This study was designed to investigate the correlation between defense mechanism and posttraumatic stress disorder in burn patients. Methods：We recruit 40 burn patients and we evaluate sociodemographic characteristics, characteristics related to... -
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- β-Patchoulene: Conversion from Patchouli Alcohol by Acid Catalysts and its In silico Anti-inflammatory Study
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F, Soekamto NH, Firdausiah S, Rasyid H, Rifai A
- KMID: 2521092
- Nat Prod Sci.
- 2021 Sep;27(3):208-215.
- doi: 10.20307/nps.2021.27.3.208
β-patchoulene (β-PAE) is a tricyclic sesquiterpene which performed many potential bioactivities and can be found in patchouli oil but in very low concentration. This study aimed to obtained β-PAE in... -
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- Fibromyalgia from the Psychiatric Perspective
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Lee Y, Lee SS, Kim H, Kim H
- KMID: 2510461
- Korean J Psychosom Med.
- 2020 Dec;28(2):99-107.
- doi: 10.22722/KJPM.2020.28.2.99
Fibromyalgia is a disorder characterized by the core symptom of chronic widespread pain, along with fa-tigue, sleep disturbances, mood changes, and cognitive difficulties. The etiology of fibromyalgia involves a combination... -
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- Temperament and Defense Mechanism Patterns of Patients with Depressive Disorder: In Comparison with or without Anxiety Symptom
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Kim JW, Yoon SH, Jo SH, Kim HG, Kang SH, Koo BH
- KMID: 2507774
- Psychoanalysis.
- 2020 Oct;31(4):70-80.
- doi: 10.18529/psychoanal.2020.31.4.70
Objectives: The objective of this study was to compare psychological characteristics in the patients of depressive disorder with or without anxiety. Methods: The study included 416 patients and divided into... -
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- Defense Mechanisms and Psychological Characteristics According to Suicide Attempts in Patients with Borderline Personality Disorder
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Lee YJ, Keum MS, Kim HG, Cheon EJ, Cho YC, Koo BH
- KMID: 2505283
- Psychiatry Investig.
- 2020 Aug;17(8):840-849.
- doi: 10.30773/pi.2020.0102
Objective There have been many biological studies on suicide behaviors of borderline personality disorder (BPD), however few studies have sought to psychoanalytic characteristics including defense mechanisms. Therefore, we investigated psychological,... -
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- Expression and Significance of MicroRNA155 in Serum of Patients with Cerebral Small Vessel Disease
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Guo Y, Li D, Li J, Yang N, Wang D
- KMID: 2504640
- J Korean Neurosurg Soc.
- 2020 Jul;63(4):463-469.
- doi: 10.3340/jkns.2019.0179
Objective : This study aimed to investigate the changes and significance of microRNA155 levels in serum of patients with cerebral small vessel disease (CSVD). Methods : Thirty patients with CSVD who... -
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- Emergence of optrA-Mediated Linezolid-Nonsusceptible Enterococcus faecalis in a Tertiary Care Hospital
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Park K, Jeong YS, Chang J, Sung H, Kim MN
- KMID: 2470329
- Ann Lab Med.
- 2020 Jul;40(4):321-325.
- doi: 10.3343/alm.2020.40.4.321
This study investigated resistance mechanisms and epidemiology of emerging linezolid-nonsusceptible Enterococcus faecalis (LNSEF) in a tertiary care hospital. LNSEF isolated from clinical samples were collected from November 2017 to June... -
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- Patella dislocation: an online systematic video analysis of the mechanism of injury
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Dewan V, Webb MSL, Prakash D, Malik A, Gella S, Kipps C
- KMID: 2506250
- Knee Surg Relat Res.
- 2020 Jun;32(2):e24.
- doi: 10.1186/s43019-020-00031-w
Background: The mechanism of injury (MoI) for a patellar dislocation has not been fully established. The aim of this study was to use systematic video analysis to determine the MoI... -
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