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Endovascular Treatment for Posterior Circulation Stroke: Ways to Maximize Therapeutic Efficacy

Lee SJ, Hong JM, Kim JS, Lee JS

The efficacy of endovascular treatment (EVT) in patients with posterior circulation stroke has not been proven. Two recent randomized controlled trials failed to show improved functional outcomes after EVT for...
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The effectiveness of systemic and endovascular intra-arterial thrombectomy protocol for decreasing door-to-recanalization time duration

Kim SC, Lee CY, Kim CH, Sohn SI, Hong JH, Park H

Objective: Variable treatment strategies and protocols have been applied to reduce time durations in the process of acute stroke management. The aim of this study is to investigate the effectiveness...
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Outcomes of Mechanical Thrombectomy in Patients with Large Diffusion-Weighted Imaging Lesions

Cho YH, Choi JH

Objective : Despite many advancements in endovascular treatment, the benefits of mechanical thrombectomy (MT) in patients with large infarctions remain uncertain due to hemorrhagic complications. Therefore, we aimed to investigate...
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Extending the stroke treatment window beyond DAWN in patients with very slow progressor type collaterals: How far can we go?

Pagiola I, Chassin O, Gallas S, Riviere MS, Legris N, Mihalea C, Caroff J, Ikka L, Chalumeau V, Aguiar GBd, Ozanne A, Moret J, Denier C, Spelle L

Five trials published in 2015 showed the benefit of endovascular thrombectomy (ET) in patients with stroke and large vessel occlusion, extending the treatment window has become an obsession of all...
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Aspiration-Retriever Technique for Stroke with Large Bore Intermediate Catheter : A Single Center Experience

Nam JW, Jung NY, Park ES, Kwon SC

Objective : Early successful reperfusion is associated with favorable outcomes in acute ischemic stroke (AIS). The purpose of this study was to achieve successful recanalization by a combined mechanical thrombectomy...
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Usefulness of three-dimensional fast imaging employing steady-state acquisition MRI of large vessel occlusion for detecting occluded middle cerebral artery and internal carotid artery before acute mechanical thrombectomy

Sato K, Hijikata Y, Omura N, Miki T, Kakita H, Yoshida T, Shimizu F

Objective: Acute mechanical thrombectomy (AMT) in patients with acute ischemic stroke from large vessel occlusion (LVO) is performed without directly identifying the occluded vessels. In this study, we evaluated whether...
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Mechanical Thrombectomy for Large Vessel Occlusion via the Transbrachial Approach: Case Series

Tsuji Y, Miki T, Kakita H, Sato K, Yoshida T, Shimizu F

Mechanical thrombectomy has become a standard treatment for acute ischemic stroke with large vessel occlusion. In aged patients, it is difficult to guide the catheter via the transfemoral approach due...
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Antiplatelet therapy within 24 hoursof tPA: lessons learned from patientsrequiring combined thrombectomyand stenting for acute ischemic stroke

Brandel MG, Elsawaf Y, Rennert RC, Steinberg JA, Santiago-Dieppa DR, Wali AR, Olson SE, Pannell JS, Khalessi AA

Objective: Although stroke guidelines recommend antiplatelets be started 24 hours after tissue plasminogen activator (tPA), select mechanical thrombectomy (MT) patients with luminal irregularities or underlying intracranial atherosclerotic disease may benefit from earlier antiplatelet...
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Predictors of Catastrophic Outcome after Endovascular Thrombectomy in Elderly Patients with Acute Anterior Circulation Stroke

Ahn Y, Kim SK, Baek BH, Lee YY, Lee HJ, Yoon W

OBJECTIVE: Avoiding a catastrophic outcome may be a more realistic goal than achieving functional independence in the treatment of acute stroke in octogenarians. This study aimed to investigate predictors of...
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Emergency management of stroke in the era of mechanical thrombectomy

Brandler E, Baksh N

Emergency management of stroke has been directed at the delivery of recombinant tissue plasminogen activator (tPA) in a timely fashion. Because of the many limitations attached to the delivery of...
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Alternative Transcarotid Approach for Endovascular Treatment of Acute Ischemic Stroke Patients: A Case Series

Styczen H, Behme D, Hesse AC, Psychogios MN

PURPOSE: Mechanical thrombectomy has become the standard of care for acute stroke caused by large vessel occlusion. As more patients are treated endovascularly, the number of older patients with tortuous...
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Long-term Prognosis of Patients Who Contraindicated for Intravenous Thrombolysis in Acute Ischemic Stroke

Lee BY, Oh JS, Yoon SM

BACKGROUND: As intravenous thrombolysis (IVT) has very restricted inclusion criteria, eligible patients of IVT constitute a very small proportion and studies about their mortality are rare. The long-term mortality in...
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Implications of Mechanical Endovascular Thrombectomy for Acute Basilar and Posterior Cerebral Artery Occlusion

Lee HN, Kim BT, Im SB, Hwang SC, Jeong JH, Chung MY, Park JH, Shin DS

OBJECTIVE: Protocols for posterior circulation ischemic stroke have not been established by randomized clinical trials. Mechanical endovascular thrombectomy (MET) devices are evolving, and many of these devices already developed or...
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Mechanical Thrombectomy in Strokes with Large-Vessel Occlusion Beyond 6 Hours: A Pooled Analysis of Randomized Trials

Vidale S, Longoni M, Valvassori L, Agostoni E

BACKGROUND AND PURPOSE: Mechanical thrombectomy with or without intravenous thrombolysis is indicated in the acute treatment of ischemic strokes caused by an emergent large-vessel occlusion (ELVO) within 6 hours from...
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Cell free DNA: A Novel Predictor of Neurological Outcome after Intravenous Thrombolysis and/or Mechanical Thrombectomy in Acute Ischemic Stroke Patients

Vajpeyee A, Wijatmiko , Vajpeyee M, Taywade O

PURPOSE: Several blood markers have been evaluated in stroke patients, but their role remains limited in clinical practice. This study was designed to evaluate the utility of cell free DNA...
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Endovascular Stroke Therapy Focused on Stent Retriever Thrombectomy and Direct Clot Aspiration: Historical Review and Modern Application

Kang DH, Park J

Intravenous recombinant tissue plasminogen activator had been the only approved treatment for acute ischemic stroke since its approval in 1995. However, the restrictive time window, numerous contraindications, and its low...
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Forced Arterial Suction Thrombectomy Using Distal Access Catheter in Acute Ischemic Stroke

Lee HC, Kang DH, Hwang YH, Kim YS, Kim YW

Historical innovations in mechanical thrombectomy devices and strategies for ischemic stroke have resulted in improved angiographic outcomes and better clinical outcomes. Various devices have been used, but the two most...
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Treatment of the Superior Sagittal Sinus Thrombosis with the Mechanical Thrombectomy Using Stent-Retriever Device

Kim H, Kim SR, Park IS, Kim YW

Cerebral venous sinus thrombosisis an uncommon entity and its clinical presentations are highly variable. We present the case of superior sagittal sinus thrombosis. Although it was medical refractory, successfully treated...
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Mechanical Solitaire Thrombectomy with Low-Dose Booster Tirofiban Injection

Goh DH, Jin SC, Jeong HW, Ha SY

PURPOSE: Mechanical thrombectomy using a Solitaire stent has been associated with a high recanalization rate and favorable clinical outcome in intra-arterial thrombolysis. To achieve a higher recanalization rate for mechanical...
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Acute Ischemic Stroke Involving Both Anterior and Posterior Circulation Treated by Endovascular Revascularization for Acute Basilar Artery Occlusion via Persistent Primitive Trigeminal Artery

Imahori T, Fujita A, Hosoda K, Kohmura E

We report a case of acute ischemic stroke involving both the anterior and posterior circulation associated with a persistent primitive trigeminal artery (PPTA), treated by endovascular revascularization for acute basilar...
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