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Transplantation of chemically induced liver progenitors as a treatment to ameliorate liver fibrosis

Fukumoto M, Hidaka M, Soyama A, Hara T, Miyamoto D, Matsuguma K, Matsushima H, Imamura H, Adachi T, Eguchi S

Background: Hepatocyte-based regenerative therapy has been reported as an alternative treatment to liver transplantation for end-stage liver disease. We have been investigating the reprogramming of mature hepatocytes to liver progenitors...
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