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miR-526b targets 3' UTR of MMP1 mRNA

Kim KH, Jung JY, Son ED, Shin DW, Noh M, Lee TR

Regulation of matrix metalloproteinases (MMPs) is important for many physiological processes involving cancers, inflammation, tissue remodeling and skin aging. Here, we report the novel finding that the expression of MMP1...
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Galectin-3 increases the motility of mouse melanoma cells by regulating matrix metalloproteinase-1 expression

Wang YG, Kim SJ, Baek JH, Lee HW, Jeong SY, Chun KH

  • KMID: 1383801
  • Exp Mol Med.
  • 2012 Jun;44(6):387-393.
Although mounting evidence indicates the involvement of galectin-3 in cancer progression and metastasis, the underlying molecular mechanisms remain largely unknown. In this study, we investigated the effect and possible mechanism...
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A functional comparison between the HER2high/HER3 and the HER2low/HER3 dimers on heregulin-beta1-induced MMP-1 and MMP-9 expression in breast cancer cells

Kim S, Han J, Shin I, Kil WH, Lee JE, Nam SJ

  • KMID: 1387358
  • Exp Mol Med.
  • 2012 Aug;44(8):473-482.
Overexpression of HER2 correlates with more aggressive tumors and increased resistance to cancer chemotherapy. However, a functional comparison between the HER2high/HER3 and the HER2low/HER3 dimers on tumor metastasis has not...
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