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New era for mucosal mast cells: their roles in inflammation, allergic immune responses and adjuvant development

Kurashima , Kiyono H

To achieve immune homeostasis in such a harsh environment as the intestinal mucosa, both active and quiescent immunity operate simultaneously. Disruption of gut immune homeostasis leads to the development of...
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Mast cells play a key role in Th2 cytokine-dependent asthma model through production of adhesion molecules by liberation of TNF-alpha

Chai OH, Han EH, Lee HK, Song CH

Mast cells are well recognized as key cells in allergic reactions, such as asthma and allergic airway diseases. However, the effects of mast cells and TNF-alpha on T-helper type 2...
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