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Correlation of Early Outcomes and Intradiscal Interleukin-6 Expression in Lumbar Fusion Patients

Koerner JD, Markova DZ, Schroeder , Antonacci , Mendelis J, Vaccaro AR, Anderson D, Kepler CK

Objective: To determine if there is correlation between intradiscal levels of interleukin-6 (IL-6) and early outcome measures in patients undergoing lumbar fusion for painful disc degeneration. Methods: Intervertebral disc tissue was...
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Inhibition of Neurogenic Inflammatory Pathways Associated with the Reduction in Discogenic Back Pain

Canseco JA, Levy HA, Karamian BA, Blaber O, Chang M, Patel N, Curran J, Hilibrand AS, Schroeder GD, Vaccaro AR, Markova DZ, Surrey DE, Kepler CK

Study Design: Retrospective cohort study. Purpose: This study aimed to determine whether the initiation of anti-calcitonin gene-related peptide (CGRP inhibitor) medication therapy for migraines was also associated with improvements in back/neck...
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