- Increased levels of multiple forms of dihydrofolate reductase in peripheral blood leucocytes of cancer patients receiving haematopoietic colony-stimulating factors: interim analysis
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Iqbal MP, Burney IA, Sultana F, Mehboobali N, Siddiqui T
- KMID: 1109307
- Exp Mol Med.
- 2000 Jun;32(2):84-87.
The precise mechanism whereby granulocytes proliferate when haematopoietic colony stimulating factors (CSFs) are used in neutropenic cancer patients is poorly understood. The purpose of this study was to investigate whether... -
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- Phosphorylation of ribosomal protein S6 and its regulation during differentiation of human leukemic cells
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Kim IS, Lee SB, Cho KC
- KMID: 1422012
- J Korean Med Sci.
- 1993 Dec;8(6):413-419.
- doi: 10.3346/jkms.1993.8.6.413
We attempted to study the role of protein tyrosine kinase (PTK) and protein kinase C (PKC) in the cascade of phosphorylation of ribosomal protein S6 during differentiation of leukemic cells... -
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- Osteoprotegerin is present on the membrane of osteoclasts isolated from mouse long bones
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Woo KM, Choi Y, Ko SH, Ko JS, Oh KO, Kim KK
- KMID: 755206
- Exp Mol Med.
- 2002 Nov;34(5):347-352.
Osteoprotegerin (OPG), a member of the tumor necrosis factor receptor superfamily, is known to inhibit osteoclastogenesis by acting as a soluble decoy receptor for the receptor activator of NF-kB ligand... -
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- Tanshinone IIA inhibits osteoclast differentiation through down-regulation of c-Fos and NFATc1
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Kwak HB, Yang D, Ha H, Lee JH, Kim HN, Woo ER, Lee S, Kim HH, Lee ZH
- KMID: 1094151
- Exp Mol Med.
- 2006 Jun;38(3):256-264.
Bone is a dynamic tissue that is regulated by the activity of bone-resorbing osteoclasts and bone-forming osteoblasts. Excessive osteoclast formation causes diseases such as osteoporosis and rheumatoid arthritis. Natural substances... -
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- Defects in the differentiation and function of bone marrow-derived dendritic cells in non-obese diabetic mice
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Lee M, Kim AY, Kang Y
- KMID: 648127
- J Korean Med Sci.
- 2000 Apr;15(2):217-223.
- doi: 10.3346/jkms.2000.15.2.217
Due to their high immunostimulatory ability as well as the critical role they play in the maintenance of self-tolerance, dendritic cells have been implicated in the pathogenesis of autoimmune diseases.... -
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- Ex vivo generation of functional dendritic cells from mobilized CD34+ hematopoietic stem cells
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Min YH, Lee ST, Choi KM, Chong SY, Kim HO, Hahn JS, Ko YW
- KMID: 711566
- Yonsei Med J.
- 1998 Aug;39(4):328-338.
- doi: 10.3349/ymj.1998.39.4.328
The ability to generate dendritic cells (DCs) in sizeable numbers has enormous implications for the development of clinically-effective antigen presentation procedures for cancer immunotherapy. We evaluated the generation of immunostimulatory... -
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