Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

PUBLICATION DATE

13 results
Display

Fucoidan Induces Apoptosis in A2058 Cells through ROS-exposed Activation of MAPKs Signaling Pathway

Ryu YS, Hyun JW, Chung HS

Fucoidan, a natural component of brown seaweed, has various biological activities such as anticancer activity, anti-oxidant, and anti-inflammatory against various cancer cells. However, the fucoidan has been implicated in melanoma...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Eupatilin downregulates phorbol 12-myristate 13-acetate-induced MUC5AC expression via inhibition of p38/ERK/JNK MAPKs signal pathway in human airway epithelial cells

Cheon YH, Kim MS, Kim JY, Kim DH, Han SY, Lee JH

Chronic inflammatory airway diseases, such as chronic rhinosinusitis, chronic obstructive pulmonary disease, and asthma, are associated with excessive mucus production. Hence, the regulation of mucus production is important for the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Transduced Tat-aldose Reductase Protects Hippocampal Neuronal Cells against Oxidative Stress-induced Damage

Cho SB, Eum WS, Shin MJ, Kwon HJ, Park JH, Choi YJ, Park J, Han KH, Kang JH, Kim DS, Cho SW, Kim DW, Choi SY

Aldose reductase (AR) protein, a member of the NADPH-dependent aldo-keto reductase family, reduces a wide range of aldehydes and enhances cell survival by inhibition of oxidative stress. Oxidative stress is...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Immunomodulating activity of Sargassum horneri extracts in RAW264.7 macrophages

Kim DS, Sung NY, Park SY, Kim G, Eom J, Yoo JG, Seo IR, Han IJ, Cho YB, Kim KA

PURPOSE: Sargassum horneri (S. horneri) is a species of brown macroalgae that is common along the coast of Japan and Korea. The present study investigated the immuno-modulatory effects of different...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Role of mitogen-activated protein kinases and nuclear factor-kappa B in 1,3-dichloro-2-propanol-induced hepatic injury

Lee IC, Lee SM, Ko JW, Park SH, Shin IS, Moon C, Kim SH, Kim JC

In this study, the potential hepatotoxicity of 1,3-dichloro-2-propanol and its hepatotoxic mechanisms in rats was investigated. The test chemical was administered orally to male rats at 0, 27.5, 55, and...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Diallyl Disulfide Prevents Cyclophosphamide-Induced Hemorrhagic Cystitis in Rats through the Inhibition of Oxidative Damage, MAPKs, and NF-kappaB Pathways

Kim SH, Lee IC, Ko JW, Moon C, Kim SH, Shin IS, Seo YW, Kim HC, Kim JC

This study investigated the possible effects and molecular mechanisms of diallyl disulfide (DADS) against cyclophosphamide (CP)-induced hemorrhagic cystitis (HC) in rats. Inflammation response was assessed by histopathology and serum cytokines...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Dexamethasone Induces Apoptosis of Nasal Polyp-Derived Tissue Cultures Through JNK and p38 MAPK Activation

Lee TH, Nam JG, Lee HM, Kim BY, Kang MK, Bae WY, Hur DY, Park SK

  • KMID: 2278384
  • Clin Exp Otorhinolaryngol.
  • 2014 Jun;7(2):112-118.
OBJECTIVES: Glucocorticoids, such as dexamethasone (DEX), increase apoptosis in a variety of white cells in nasal polyps and apoptosis is an important factor in the resolution of inflammation. However, the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Characterization of Proinflammatory Responses and Innate Signaling Activation in Macrophages Infected with Mycobacterium scrofulaceum

Kim KH, Kim TS, Lee JG, Park JK, Yang M, Kim JM, Jo EK, Yuk JM

Mycobacterium scrofulaceum is an environmental and slow-growing atypical mycobacterium. Emerging evidence suggests that M. scrofulaceum infection is associated with cervical lymphadenitis in children and pulmonary or systemic infections in immunocompromised...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Mitogen-activated Protein Kinases in Inflammation

Manzoor Z, Koh YS

Mitogen-activated protein kinases (MAPKs) play critical regulatory roles in the production of the pro-inflammatory cytokines and downstream signaling events which lead to inflammation. Inflammation is a primarily localized and protective...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Dendritic Cell Activation by Glucan Isolated from Umbilicaria Esculenta

Kim HS, Kim JY, Lee HK, Kim MS, Lee SR, Kang JS, Kim HM, Lee KA, Hong JT, Kim Y, Han SB

BACKGROUND: Lichen-derived glucans have been known to stimulate the functions of immune cells. However, immunostimulatory activity of glucan obtained from edible lichen, Umbilicaria esculenta, has not been reported. Thus we...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
TNF-alpha-induced Increase of Human beta-defensin-2 Expression in HaCaT Cell Lines

Park YD, Lee KS

  • KMID: 2248097
  • Korean J Dermatol.
  • 2008 Jul;46(7):867-873.
BACKGROUND: Several kinds of epithelial cells and focal lymph nodes are known to be involved in the skin's immune reaction. Especially, internal antimicrobial peptide play an important role in protecting...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Immunohistochemical Study of MAPKs Expression in Psoriatic Epidermis

Kim SH, Ko JH, Choi KC, Chung BS

No abstract available.
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Role of sphingomyelin-MAPKs pathway in heat-induced apoptosis

Chung HS, Park SR, Choi EK, Park HJ, Griffin RJ, Song CW, Park H

  • KMID: 1094699
  • Exp Mol Med.
  • 2003 Jun;35(3):181-188.
The role of sphingomyelinase (SMase) activation and mitogen activated protein kinases (MAPKs) activation in cellular apoptosis was investigated during the hyperthermic treatment of HL-60 human leukemia cells. Treating the cells...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr