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Cysteine-179 of I kappa B kinase beta plays a critical role in enzyme activation by promoting phosphorylation of activation loop serines

Byun MS, Choi J, Jue DM

  • KMID: 1098089
  • Exp Mol Med.
  • 2006 Oct;38(5):546-552.
I kappa B kinase beta (IKK beta) subunit of IKK complex is essential for the activation of NF-kappa B in response to various proinflammatory signals. Cys-179 in the activation loop...
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LL-37 inhibits serum amyloid A-induced IL-8 production in human neutrophils

Lee HY, Kim SD, Shim JW, Lee SY, Yun J, Bae YS

Serum amyloid A (SAA) has been regarded as an important mediator of inflammatory responses. The effect of several formyl peptide receptor-like 1 (FPRL1) ligands on the production of IL-8 by...
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